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Ankylosing spondylitis (AS) is a form of arthritis that primarily affects the spine, although other joints can become involved. It causes inflammation of the spinal joints (vertebrae) that can lead to severe, chronic pain and discomfort.
The inflammatory mediators of RA including cytokines, growth factors, metalloproteinases destroy articular cartilage, subchondral bone, tendons and ligaments. Destructive synovitis leads to bone erosion and causes the ligaments of the spine to become too laxed (loose), eventually resulting in cervical spinal instability (loose neck bones). [6]
Pain is often severe at rest but may improve with physical activity. Inflammation and pain may recur to varying degrees regardless of rest and movement. AS can occur in any part of the spine or the entire spine, often with pain localized to either buttock or the back of the thigh from the sacroiliac joint. Arthritis in the hips and shoulders ...
Arthritis is a common acute or chronic condition affecting the joints and surrounding tissues. It’s estimated that roughly 18 percent of American adults have some form of arthritis. And about 44 ...
Arthritis is a form of arthropathy that involves inflammation of one or more joints, [3] [4] while the term arthropathy may be used regardless of whether there is inflammation or not. Joint diseases can be classified as follows: [citation needed] Arthritis; Infectious arthritis; Septic arthritis (infectious) Tuberculosis arthritis; Reactive ...
Arthritis is a term often used to mean any disorder that affects joints. [2] Symptoms generally include joint pain and stiffness. [2] Other symptoms may include redness, warmth, swelling, and decreased range of motion of the affected joints.
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