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The inflammatory mediators of RA including cytokines, growth factors, metalloproteinases destroy articular cartilage, subchondral bone, tendons and ligaments.Destructive synovitis leads to bone erosion and causes the ligaments of the spine to become too laxed (loose), eventually resulting in cervical spinal instability (loose neck bones).
Ankylosing spondylitis (AS) is a form of arthritis that primarily affects the spine, although other joints can become involved. It causes inflammation of the spinal joints (vertebrae) that can lead to severe, chronic pain and discomfort.
Arthritis is a common acute or chronic condition affecting the joints and surrounding tissues. It’s estimated that roughly 18 percent of American adults have some form of arthritis. And about 44 ...
Inflammatory arthritis is a group of diseases which includes: rheumatoid arthritis, psoriatic arthropathy, inflammatory bowel disease, adult-onset Still's disease, scleroderma, juvenile idiopathic arthritis, and systemic lupus erythematosus (SLE).
The signs and symptoms of ankylosing spondylitis often appear gradually, with peak onset between 20 and 30 years of age. [11] Initial symptoms are usually a chronic dull pain in the lower back or gluteal region combined with stiffness of the lower back. [12] Individuals often experience pain and stiffness that awakens them in the early morning ...
Arthritis is a form of arthropathy that involves inflammation of one or more joints, [3] [4] while the term arthropathy may be used regardless of whether there is inflammation or not. Joint diseases can be classified as follows: [citation needed] Arthritis; Infectious arthritis; Septic arthritis (infectious) Tuberculosis arthritis; Reactive ...
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