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Peeling skin syndrome 1. Peeling skin syndrome 1 is caused by a genetic defect in the corneodesmosin (CDSN) gene. This gene localizes to the human epidermis and other epithelia. The protein experiences a chain of cleavages during corneocyte maturation. [6] Its symptoms include short stature, abnormality of metabolism/homeostasis, scaling skin ...
Scale forms on the skin surface in various disease settings, and is the result of abnormal desquamation. In pathologic desquamation, such as that seen in X-linked ichthyosis, the stratum corneum becomes thicker (hyperkeratosis), imparting a "dry" or scaly appearance to the skin, and instead of detaching as single cells, corneocytes are shed in clusters, which forms visible scales. [2]
HCMUT is a member of Vietnam National University, Ho Chi Minh City. It focuses on high technology and engineering. It is one of the officially key universities in Vietnam. The predecessor of HCMUT was the National Institute of Technology, established in 1957 by the South Vietnam. [ 2] The institute was renamed National Academy of Technology in ...
Psoriasis. Psoriasis is a long-lasting, noncontagious autoimmune disease characterized by patches of abnormal skin. [ 4][ 5] These areas are red, pink, or purple, dry, itchy, and scaly. [ 8][ 3] Psoriasis varies in severity from small localized patches to complete body coverage. [ 3] Injury to the skin can trigger psoriatic skin changes at that ...
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Voxelotor was granted accelerated approval by the U.S. Food and Drug Administration (FDA) in November 2019. [12] [11] [15] The FDA granted the application for voxelotor fast track designation and orphan drug designation.
Search for. Structures. Swiss-model. Domains. InterPro. Transporter associated with antigen processing ( TAP) protein complex belongs to the ATP-binding-cassette transporter family. [ 1] It delivers cytosolic peptides into the endoplasmic reticulum (ER), where they bind to nascent MHC class I molecules. [ 2] The TAP structure is formed of two ...
Cheilitis is a medical condition characterized by inflammation of the lips. The inflammation may include the perioral skin (the skin around the mouth), the vermilion border, or the labial mucosa. [ 1] The skin and the vermilion border are more commonly involved, as the mucosa is less affected by inflammatory and allergic reactions.