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  2. Grapefruit–drug interactions - Wikipedia

    en.wikipedia.org/wiki/Grapefruitdrug_interactions

    The relative risks of different types of citrus fruit have not been systematically studied. [1] Affected drugs typically have an auxiliary label saying "Do not take with grapefruit" on the container, and the interaction is elaborated upon in the package insert. [6] People are advised to ask their physician or pharmacist about drug interactions. [6]

  3. Grapefruit can interfere with your medications — here's what ...

    www.aol.com/lifestyle/grapefruit-interfere...

    That's because the popular citrus fruit shouldn't be combined with certain medications. ... "Many food-drug interactions and potential side effects can be avoided by following certain precautions ...

  4. Naringenin - Wikipedia

    en.wikipedia.org/wiki/Naringenin

    Taking dietary supplements or consuming grapefruit excessively may impair the action of anticoagulants and increase the toxicity of various prescription drugs. [2] Similar to furanocoumarins present in citrus fruits, naringenin may evoke CYP3A4 suppression in the liver and intestines, possibly resulting in adverse interactions with common ...

  5. Grapefruit - Wikipedia

    en.wikipedia.org/wiki/Grapefruit

    In the past it was called the pomelo, [3] but that term is now mostly used as the common name for Citrus maxima. [4] Grapefruit–drug interactions are common, as the juice contains furanocoumarins that interfere with the metabolism of many drugs. This can prolong and intensify the effects of those drugs, leading to multiple side-effects such ...

  6. Can grapefruit boost your immune system and help you lose ...

    www.aol.com/news/grapefruit-boost-immune-system...

    The citrus gets a lot of buzz during cold and flu season and weight-loss season as people look for ways to be healthy in the new year. But can eating grapefruit really help boost the immune system ...

  7. Naringin - Wikipedia

    en.wikipedia.org/wiki/Naringin

    Naringin is a flavanone-7-O-glycoside between the flavanone naringenin and the disaccharide neohesperidose.The flavonoid naringin occurs naturally in citrus fruits, especially in grapefruit, where naringin is responsible for the fruit's bitter taste.

  8. What Is the Safest ED Medication? - AOL

    www.aol.com/safest-ed-medication-105700669.html

    Citrus fruits, such as orange, grapefruit, lemon and lime Other fresh fruits, including kiwifruit, guava and papaya Strawberries, blackberries, raspberries and blueberries

  9. CYP3A4 - Wikipedia

    en.wikipedia.org/wiki/CYP3A4

    The effect of grapefruit juice with regard to drug absorption was originally discovered in 1989. The first published report on grapefruit drug interactions was in 1991 in the Lancet entitled "Interactions of Citrus Juices with Felodipine and Nifedipine", and was the first reported food-drug interaction clinically. The effects of grapefruit last ...