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  2. Silent mutation - Wikipedia

    en.wikipedia.org/wiki/Silent_mutation

    Silent mutations, also called synonymous or samesense mutations, are mutations in DNA that do not have an observable effect on the organism's phenotype. The phrase silent mutation is often used interchangeably with the phrase synonymous mutation ; however, synonymous mutations are not always silent, nor vice versa.

  3. Synonymous substitution - Wikipedia

    en.wikipedia.org/wiki/Synonymous_substitution

    Point substitution mutations of a codon, classified by their impact on protein sequence. A synonymous substitution (often called a silent substitution though they are not always silent) is the evolutionary substitution of one base for another in an exon of a gene coding for a protein, such that the produced amino acid sequence is not modified.

  4. Single-nucleotide polymorphism - Wikipedia

    en.wikipedia.org/wiki/Single-nucleotide_polymorphism

    An example would be a seemingly silent mutation in the multidrug resistance gene 1 , which codes for a cellular membrane pump that expels drugs from the cell, can slow down translation and allow the peptide chain to fold into an unusual conformation, causing the mutant pump to be less functional (in MDR1 protein e.g. C1236T polymorphism changes ...

  5. Genetic divergence - Wikipedia

    en.wikipedia.org/wiki/Genetic_divergence

    The genetic differences among divergent populations can involve silent mutations (that have no effect on the phenotype) or give rise to significant morphological and/or physiological changes. Genetic divergence will always accompany reproductive isolation, either due to novel adaptations via selection and/or due to genetic drift, and is the ...

  6. Mutagen - Wikipedia

    en.wikipedia.org/wiki/Mutagen

    Many mutations are silent mutations, causing no visible effects at all, either because they occur in non-coding or non-functional sequences, or they do not change the amino-acid sequence due to the redundancy of codons. [33] Some mutagens can cause aneuploidy and change the number of chromosomes in the cell. They are known as aneuploidogens. [34]

  7. Bird flu virus shows mutations in first severe human case in ...

    www.aol.com/news/bird-flu-virus-shows-mutations...

    The CDC said the patient's sample showed mutations in the hemagglutinin (HA) gene, the part of the virus that plays a key role in it attaching to host cells. The mutations seen in the patient are ...

  8. Nonsynonymous substitution - Wikipedia

    en.wikipedia.org/wiki/Nonsynonymous_substitution

    A nonsynonymous substitution is a nucleotide mutation that alters the amino acid sequence of a protein.Nonsynonymous substitutions differ from synonymous substitutions, which do not alter amino acid sequences and are (sometimes) silent mutations.

  9. Buckle up, Little Monsters. More Lady Gaga music is on the way!. In an interview with Los Angeles Times published on Thursday, Dec. 19, the A Star Is Born actress teased her upcoming album, which ...