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  2. Shifts in brain activity may signal Alzheimer's long before ...

    www.aol.com/shifts-brain-activity-may-signal...

    Subtle changes in brain activity in the presence of both amyloid-beta and tau proteins may point to Alzheimer's disease, long before symptoms appear, a new study indicates.

  3. Amyloid plaques - Wikipedia

    en.wikipedia.org/wiki/Amyloid_plaques

    Two amyloid plaques from the brain of a patient with Alzheimer's disease. In this photomicrograph, neurites are darkly stained with the Naoumenko-Feigin silver method, and the pink elements (including the plaque cores) are stained with the periodic acid-Schiff (PAS) counterstain. The bar is 20 microns (0.02 mm) in length.

  4. Alzheimer's disease - Wikipedia

    en.wikipedia.org/wiki/Alzheimer's_disease

    The causes of Alzheimer's disease remain poorly understood. [16] There are many environmental and genetic risk factors associated with its development. The strongest genetic risk factor is from an allele of apolipoprotein E. [17] [18] Other risk factors include a history of head injury, clinical depression, and high blood pressure. [1]

  5. New study challenges amyloid-beta theory on cause for ... - AOL

    www.aol.com/study-challenges-amyloid-beta-theory...

    A main theory behind the cause of Alzheimer’s disease is the build-up of the protein amyloid-beta in the brain. Researchers from the University of Cincinnati provide evidence suggesting it’s ...

  6. Study challenges current views about toxic plaque formation ...

    www.aol.com/study-challenges-current-views-toxic...

    New research is contradicting previously held views that only neurons secret beta-amyloid that forms toxic plaques, a marker of Alzheimer's disease in the brain. The study points to another ...

  7. Biochemistry of Alzheimer's disease - Wikipedia

    en.wikipedia.org/wiki/Biochemistry_of_Alzheimer's...

    The biochemistry of Alzheimer's disease, the most common cause of dementia, is not yet very well understood. Alzheimer's disease (AD) has been identified as a proteopathy : a protein misfolding disease due to the accumulation of abnormally folded amyloid beta (Aβ) protein in the brain . [ 1 ]

  8. Amyloid beta - Wikipedia

    en.wikipedia.org/wiki/Amyloid_beta

    Amyloid beta (Aβ, Abeta or beta-amyloid) denotes peptides of 36–43 amino acids that are the main component of the amyloid plaques found in the brains of people with Alzheimer's disease. [2] The peptides derive from the amyloid-beta precursor protein (APP), which is cleaved by beta secretase and gamma secretase to yield Aβ in a cholesterol ...

  9. Some people have Alzheimer’s without symptoms: What ... - AOL

    www.aol.com/lifestyle/people-alzheimer-without...

    Amyloid deposition in the brain starts decades before the onset of Alzheimer’s symptoms. One study found that 44% of 90-year-olds with good cognitive function had amyloid pathology ,” Hara ...

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