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About 60% of the metronidazole is metabolized by oxidation to the main metabolite hydroxymetronidazole and a carboxylic acid derivative, and by glucuronidation. The metabolites show antibiotic and antiprotozoal activity in vitro. [62] Metronidazole and its metabolites are mainly excreted via the kidneys (77%) and to a lesser extent via the ...
The drug must not be taken by pregnant women, because tetracycline is known to cause tooth and bone defects in unborn children. It is also contraindicated in breastfeeding women, children up to 12 years of age, and by patients with impaired liver or renal (kidney) function, because no studies in such persons have been conducted.
RELATED: 5 Effects of Not Brushing Your Teeth If collected and properly stored, baby teeth could be used to potentially treat and cure a life-threatening illness a child or a close family member ...
In areas of low clarithromycin resistance, including the United States, a 14-day course of "triple therapy" with an oral proton pump inhibitor, clarithromycin 500 mg, and amoxicillin 1 g (or, if penicillin allergic, metronidazole 500 mg), all given twice daily for 14 days, is recommended for first-line therapy. This regimen can achieve rates of ...
For people who are symptomatic, it is used after treatment with metronidazole or tinidazole. [2] It is taken by mouth. [1] Diloxanide generally has mild side effects. [3] Side effects may include flatulence, vomiting, and itchiness. [1] During pregnancy it is recommended that it be taken after the first trimester. [1]
metronidazole 500–750 mg three times a day for 5–10 days; tinidazole 2g once a day for 3 days is an alternative to metronidazole; Doses for children are calculated by body weight and a pharmacist should be consulted for help.
Cannabis use during pregnancy should be avoided. [80] There is no known safe dose of cannabis while pregnant and use of cannabis may lead to birth defects, pre-term birth, or low birth weight. [80] Tetrahydrocannabinol (THC), an active ingredient in cannabis, can both cross the placenta and accumulates in high concentrations in breast milk. [81]
Although tooth eruption occurs at different times for different people, a general eruption timeline exists. The tooth buds of baby teeth start to develop around 6 weeks of pregnancy. Adult teeth buds start forming around 4 months of pregnancy. The entire tooth will start to form from the crown down to the root. [8]