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The Reproducibility Project is a series of crowdsourced collaborations aiming to reproduce published scientific studies, finding high rates of results which could not be replicated. It has resulted in two major initiatives focusing on the fields of psychology [ 1 ] and cancer biology. [ 2 ]
Considerations about reproducibility can be placed into two categories. Reproducibility in the narrow sense refers to re-examining and validating the analysis of a given set of data. Replication refers to repeating the experiment or study to obtain new, independent data with the goal of reaching the same or similar conclusions.
In 2011, Nosek and his collaborators set up the Reproducibility Project, with the aim of trying to replicate the results of 100 psychological experiments published in respected journals in 2008. [4] In 2015, their results were published in Science , and found that only 36 out of the 100 replications showed statistically significant results ...
The organization began with work in reproducibility of psychology research, with the large-scale initiative Reproducibility Project: Psychology. [3] [4] [5] A second reproducibility project for cancer biology research has also been started through a partnership with Science Exchange. [6] In March 2017, the Center published a detailed strategic ...
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In 2021, another Reproducibility Project, Cancer Biology, analyzed 53 top papers about cancer published between 2010 and 2012 and established that the effect sizes were 85% smaller on average than the original findings . [38] During the 2010s, the concept of reproducibility crisis has been expanded to a wider array of disciplines.