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An integral, or intrinsic, membrane protein (IMP) [1] is a type of membrane protein that is permanently attached to the biological membrane. All transmembrane proteins can be classified as IMPs, but not all IMPs are transmembrane proteins. [ 2 ]
Comparison of transport proteins A symporter is an integral membrane protein that is involved in the transport of two (or more) different molecules across the cell membrane in the same direction. The symporter works in the plasma membrane and molecules are transported across the cell membrane at the same time, and is, therefore, a type of ...
Depending on the number of transmembrane segments, transmembrane proteins can be classified as single-pass membrane proteins, or as multipass membrane proteins. [2] Some other integral membrane proteins are called monotopic, meaning that they are also permanently attached to the membrane, but do not pass through it. [3]
the F o domain, which is integral in the membrane and is composed of 3 different types of integral proteins classified as a, b and c. [1] the F 1, which is peripheral (on the side of the membrane that the protons are moving into). F 1 is composed of 5 polypeptide units α3β3γδε that bind to the surface of the F o domain. [1]
[13] [16] Detergents can be used to render membrane proteins water-soluble, but these can also alter protein structure and function. [13] Making membrane proteins water-soluble can also be achieved through engineering the protein sequence, replacing selected hydrophobic amino acids with hydrophilic ones, taking great care to maintain secondary ...
Protein channel proteins, also called permeases, are usually quite specific, and they only recognize and transport a limited variety of chemical substances, often limited to a single substance. Another example of a transmembrane protein is a cell-surface receptor, which allow cell signaling molecules to communicate between cells.
A comparison of transport proteins [1]. An antiporter (also called exchanger or counter-transporter) is an integral membrane protein that uses secondary active transport to move two or more molecules in opposite directions across a phospholipid membrane.
Also known as water channels, aquaporins are integral membrane pore proteins. Some of them, known as aquaglyceroporins, also transport other small uncharged dissolved molecules including ammonia, CO 2, glycerol, and urea.