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Periorbital dark circles. Minor dark circles and a hint of periorbital puffiness —a combination principally suggestive of minor sleep deprivation. Periorbital dark circles (including dark circles of the lower eyelid) are dark blemishes around the eyes. There are many causes of this symptom, including heredity and bruising.
Ophthalmology. Ocular melanosis ( OM) is a blue-gray and/or brown lesion of the conjunctiva that can be separated into benign conjunctival epithelial melanosis ( BCEM) and primary acquired melanosis ( PAM ), of which the latter is considered a risk factor for uveal melanoma. [1] The disease is caused by an increase of melanocytes in the iris ...
Periorbital hyperpigmentation, also known as hereditary dark circles, is characterized by darker skin around the eyes caused by the presence of additional melanin. It is an extremely common hereditary human characteristic and is frequently found on individuals with dark skin. Periorbital hyperpigmentation is most prevalent within the 16–25 ...
Waardenburg syndrome is a group of rare genetic conditions characterised by at least some degree of congenital hearing loss and pigmentation deficiencies, which can include bright blue eyes (or one blue eye and one brown eye ), a white forelock or patches of light skin. These basic features constitute type 2 of the condition; in type 1, there ...
Macular degeneration, also known as age-related macular degeneration ( AMD or ARMD ), is a medical condition which may result in blurred or no vision in the center of the visual field. [1] Early on there are often no symptoms. [1] Over time, however, some people experience a gradual worsening of vision that may affect one or both eyes. [1]
Heřmanský–Pudlák syndrome (often written Hermansky–Pudlak syndrome or abbreviated HPS) is an extremely rare autosomal recessive [1] disorder which results in oculocutaneous albinism (decreased pigmentation ), bleeding problems due to a platelet abnormality ( platelet storage pool defect ), and storage of an abnormal fat-protein compound ...
Lethal white syndrome ( LWS ), also called overo lethal white syndrome ( OLWS ), lethal white overo ( LWO ), and overo lethal white foal syndrome ( OLWFS ), is an autosomal genetic disorder most prevalent in the American Paint Horse. Affected foals are born after the full 11-month gestation and externally appear normal, though they have all ...
Jaundice, also known as icterus, is a yellowish or greenish pigmentation of the skin and sclera due to high bilirubin levels. [3] [6] Jaundice in adults is typically a sign indicating the presence of underlying diseases involving abnormal heme metabolism, liver dysfunction, or biliary-tract obstruction. [7]
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