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The C-terminal half of 2'-5'-oligoadenylate synthetase, also referred to as domain 2 of the enzyme, is largely alpha-helical and homologous to a tandem ubiquitin repeat. It carries the region of enzymatic activity between [clarification needed] at the extreme C-terminal end. [2]
Although economic indicators have been improving since 2014 – growth of 2.3 percent in 2023, well above the European average (0.5 percent), an unemployment rate of 6.5 percent and public debt falling below 100 percent of gross domestic product – discontent prevailed in Portugal, particularly due to the lack of response to social issues.
De Pernas pro Ar (Portuguese for Upside Down) is a 2010 Brazilian comedy film directed by Roberto Santucci. The film had its premiere on December 25, 2010, with official debut on December 31, 2010. Its sequel, De Pernas pro Ar 2, debuted in Brazilian theaters on 28 December 2012. [4]
Three ships of the Sa'ar 5 class have been built: INS Eilat, launched February 1993 INS Lahav, launched August 1993 INS Hanit, launched March 1994 The ships' missile systems include: (i) anti-air capability with 1 x 32-cell vertical launch system (although it is possible to carry another), with Barak-1 and/or Barak-8 missiles of IAI and Rafael, and two four-cell Boeing Harpoon missile launchers.
A 2.5 L version of the AR family, first released in the RAV4 in the U.S. and Canada in 2008. [3] This engine also replaced the 2AZ-FE in the U.S. and Canada Camry in early 2009, giving 11% better fuel economy. [4] The engine service mass is 324 lb (147 kg) that includes the oil and coolant fully filled.
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Al-Andalus [a] (Arabic: الأَنْدَلُس) was the Muslim-ruled area of the Iberian Peninsula.The term is used by modern historians for the former Islamic states in modern-day Gibraltar, Portugal, Spain, and Southern France.
5α-Reductase type 2 (5αR2) is an enzyme, encoded by the SRD5A2 gene, that is expressed in specific tissues in the male body from fetal development to adulthood. [4] [6] [7] The enzyme catalyzes the transformation of testosterone (T) to 5α-dihydrotestosterone (DHT) intracellularly.