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The average ratio of estradiol to estrone with vaginal estradiol is 5:1, compared to 1:5 in the case of oral estradiol, a 10-fold difference. [ 10 ] As vaginal estradiol is not subject to a first pass and bypasses the intestines and liver, it does not affect liver protein synthesis at menopausal replacement dosages, similarly to transdermal ...
[5] [3] [1] [2] [8] Topical gels are more stable than creams and ointments, and can adhere well to the site of application. [5] [2] They form an occlusive layer on the application site that can act as a form of protection. [5] They can be washed off easily and are nontoxic due to their unique composition and structure.
Casting out nines is any of three arithmetical procedures: [ 1] Adding the decimal digits of a positive whole number, while optionally ignoring any 9s or digits which sum to 9 or a multiple of 9. The result of this procedure is a number which is smaller than the original whenever the original has more than one digit, leaves the same remainder ...
Care must be taken with the signs of the remainders also. The general term is b i = r i − 1 , c i + 1 − ∑ j = 2 i b i − j + 1 × a j a 1 with remainder r i {\displaystyle b_{i}={\frac {r_{i-1},c_{i+1}-\textstyle \sum _{j=2}^{i}b_{i-j+1}\times a_{j}}{a_{1}}}{\mbox{ with remainder }}r_{i}}
A molecular-weight size marker in the form of a 1 kb DNA ladder in the rightmost lane, used in gel electrophoresis. Gel conditions are 1% agarose, 3 volt /cm, and ethidium bromide stain. A molecular-weight size marker, also referred to as a protein ladder, DNA ladder, or RNA ladder, is a set of standards that are used to identify the ...
and −2 is the least absolute remainder. In the division of 42 by 5, we have: 42 = 8 × 5 + 2, and since 2 < 5/2, 2 is both the least positive remainder and the least absolute remainder. In these examples, the (negative) least absolute remainder is obtained from the least positive remainder by subtracting 5, which is d. This holds in general ...
The misdirection in this riddle is in the second half of the description, where unrelated amounts are added together and the person to whom the riddle is posed assumes those amounts should add up to 30, and is then surprised when they do not — there is, in fact, no reason why the (10 − 1) × 3 + 2 = 29 sum should add up to 30.
The period of c / k , for c coprime to k, equals the period of 1 / k . If k = 2 a ·5 b n where n > 1 and n is not divisible by 2 or 5, then the length of the transient of 1 / k is max(a, b), and the period equals r, where r is the multiplicative order of 10 mod n, that is the smallest integer such that 10 r ≡ 1 (mod n).