Search results
Results from the WOW.Com Content Network
Sirtuin 1, also known as NAD-dependent deacetylase sirtuin-1, is a protein that in humans is encoded by the SIRT1 gene. [5] [6] [7]SIRT1 stands for sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae), referring to the fact that its sirtuin homolog (biological equivalent across species) in yeast (Saccharomyces cerevisiae) is Sir2.
SIRT1 protein promotes homologous recombination in human cells and is involved in recombinational repair of DNA breaks. [ 29 ] SIRT6 is a chromatin -associated protein and in mammalian cells is required for base excision repair of DNA damage . [ 30 ]
UniProt Archive (UniParc) is a comprehensive and non-redundant database, which contains all the protein sequences from the main, publicly available protein sequence databases. [17] Proteins may exist in several different source databases, and in multiple copies in the same database.
11545 Ensembl ENSG00000143799 ENSMUSG00000026496 UniProt P09874 P11103 RefSeq (mRNA) NM_001618 NM_007415 RefSeq (protein) NP_001609 NP_001609.2 n/a Location (UCSC) Chr 1: 226.36 – 226.41 Mb Chr 1: 180.4 – 180.43 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Poly [ADP-ribose] polymerase 1 (PARP-1) also known as NAD + ADP-ribosyltransferase 1 or poly[ADP-ribose] synthase 1 is an ...
"Hearst Magazines and Yahoo may earn commission or revenue on some items through these links." Sugar-sweetened beverages may increase your risk for heart disease and type 2 diabetes, new research ...
Legend and Teigen are parents to daughters Luna, 8, and Esti, 2, and sons Miles, 6, and Wren, 1. “Every time nature shows its wrath, we wonder if it’s time to head back east.
Bands used for smart watches and fitness trackers contain a synthetic rubber made with PFAS — also known as “forever chemicals” — and researchers are warning that these may be absorbed ...
SRT-1720 is an experimental drug that was studied by Sirtris Pharmaceuticals intended as a small-molecule activator of the sirtuin subtype SIRT1. The compound has been studied in animals, but safety and efficacy in humans have not been established.