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The tables below contain a sample list of benzodiazepines and benzodiazepine analogs that are commonly prescribed, with their basic pharmacological characteristics, such as half-life and equivalent doses to other benzodiazepines, also listed, along with their trade names and primary uses.
The "benzo" prefix indicates the benzene ring fused onto the diazepine ring. [197] Benzodiazepine drugs are substituted 1,4-benzodiazepines, although the chemical term can refer to many other compounds that do not have useful pharmacological properties. Different benzodiazepine drugs have different side groups attached to this central structure.
A study of 50 patients who attended a benzodiazepine withdrawal clinic found that, after several years of chronic benzodiazepine use, a large portion of patients developed health problems including agoraphobia, irritable bowel syndrome, paraesthesiae, increasing anxiety, and panic attacks, which were not preexisting. The mental health and ...
[4] [5] Bromazolam is a non subtype selective agonist at the benzodiazepine site of GABA A receptors, with a binding affinity of 2.81 nM at the α 1 subtype, 0.69 nM at α 2 and 0.62 nM at α 5. [6] The "common" dosage range for users of bromazolam was reported to be 1–2 mg, suggesting its potency is similar to alprazolam.
A study into the effects of the benzodiazepine receptor antagonist, flumazenil, on benzodiazepine withdrawal symptoms persisting after withdrawal was carried out by Lader and Morton. Study subjects had been benzodiazepine-free for between one month and five years, but all reported persisting withdrawal effects to varying degrees.
Calf Studio Gear, often referred to as Calf Plugins, is a set of open source LV2 plugins for the Linux platform. The suite intends to be a complete set of plugins for audio mixing, virtual instruments and mastering. As of version 0.90.0 there are 47 plugins in the suite.
Benzodiazepine abuse is steadily increasing and is now a major public health problem. Benzodiazepine abuse is mostly limited to individuals who abuse other drugs, i.e. poly-drug abusers. Most prescribed users do not abuse their medication, however, some high dose prescribed users do become involved with the illicit drug scene.
Protracted benzodiazepine withdrawal has been observed to occur in some individuals prescribed benzodiazepines. [ 8 ] [ 9 ] Drug use, including alcohol and prescription drugs, can induce symptomatology which resembles mental illness.