Search results
Results from the WOW.Com Content Network
Continuing sertraline treatment helps prevent relapses of OCD with long-term data supporting its use for up to 24 months. [50] The sertraline dosages necessary for the effective treatment of OCD are higher than the usual dosage for depression. [51] The onset of action is also slower for OCD than for depression.
This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification. Chemical/generic names are listed first, with brand names in parentheses.
Based on this percentage, free concentrations of sertraline would be 2.49 ng/mL (8.13 nM) at the very most, which is only about one-third of the K i value that Tatsumi et al. found with sertraline at the DAT. [8] A very high dosage of sertraline of 400 mg/day has been found to produce peak plasma concentrations of about 250 ng/mL (816 nM). [16]
SSRIs are modern antidepressants often used as a first-line treatment for major depressive disorder. Common SSRIs include Prozac (fluoxetine), Zoloft (sertraline) and Lexapro (escitalopram ...
Saphris – atypical antipsychotic used to treat schizophrenia and bipolar disorder; Serax – anti-anxiety medication of the benzodiazepine class, often used to help during detoxification from alcohol or other addictive substances; Serentil (mesoridazine) – an antipsychotic drug used in the treatment of schizophrenia [1]
Dosage range (mg/day) [4] ~80% SERT occupancy (mg/day) [5] [6] Ratio (dosage / 80% occupancy) Citalopram: 20–40: 40: 0.5–1 Escitalopram: 10–20: 10: 1–2 Fluoxetine: 20–80: 20: 1–4 Fluvoxamine: 50–350: 70: 0.71–5 Paroxetine: 10–60: 20: 0.5–3 Sertraline: 25–200: 50: 0.5–4 Duloxetine: 20–120: 30: 0.67–2 Venlafaxine: 75 ...
Higher dosage does, however, increase the incidence and severity of adverse events associated with excessive 5-HT re-uptake inhibition. [ 6 ] Figure 2 Inhibition of re-uptake transport proteins, e.g. SERT, results in increased concentration of neurotransmitters, e.g. 5-HT, in the synaptic cleft, leading to improvement of depression symptoms
Paroxetine has slightly higher response and remission rates for PTSD than sertraline, but both are not fully effective for many patients. [citation needed] [24] Fluoxetine is used off-label, but with mixed results; venlafaxine, an SNRI, is considered somewhat effective, although its use is also off-label. Fluvoxamine, escitalopram and ...