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The amygdala is one of the best-understood brain regions with regard to differences between the sexes. The amygdala is larger in males than females, in children aged 7 to 11, [17] adult humans, [18] and adult rats. [19] There is considerable growth within the first few years of structural development in both male and female amygdalae. [20]
The amygdala connects to the thalamus both through the amygdalofugal pathway and through a direct connection to the dorsomedial nucleus of the thalamus. [13] After leaving the substantia innominata , the ventral amygdalofugal pathway continues on a medial path to enter the septal region, the lateral preoptic area , the hypothalamus , and the ...
The basolateral amygdala and nucleus accumbens shell together mediate specific Pavlovian-instrumental transfer, a phenomenon in which a classically conditioned stimulus modifies operant behavior. [7] [8] One of the main functions of the basolateral complex is to stimulate the fear response. The fear system is intended to avoid pain or injury.
The uncinate fasciculus is a white matter association tract in the human brain that connects parts of the limbic system such as the temporal pole, anterior parahippocampus, and amygdala in the temporal lobe with inferior portions of the frontal lobe such as the orbitofrontal cortex.
S.M., sometimes referred to as SM-046, is an American woman with a peculiar type of brain damage that physiologically reduces her ability to feel fear.First described by scientists in 1994, [1] she has had exclusive and complete bilateral amygdala destruction since late childhood as a consequence of Urbach–Wiethe disease.
Besides memory, the amygdala also seems to be an important brain region involved in attentional and emotional processes. First, to define attention in cognitive terms, attention is the ability to focus on some stimuli while ignoring others. Thus, the amygdala seems to be an important structure in this ability.
Amygdalotomy, also known as amygdalectomy, is a form of psychosurgery which involves the surgical removal or destruction of the amygdala, or parts of the amygdala.It is usually a last-resort treatment for severe aggressive behavioral disorders and similar behaviors including hyperexcitability, violent outbursts, and self-mutilation.
Inputs and outputs of the rodent central amygdala. The regions described as amygdala nuclei encompass several structures with distinct connectional and functional characteristics in humans and other animals. [9] Among these nuclei are the basolateral complex, the cortical nucleus, the medial nucleus, and the central nucleus. The basolateral ...