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  2. Needlestick injury - Wikipedia

    en.wikipedia.org/wiki/Needlestick_injury

    A needlestick injury is the penetration of the skin by a hypodermic needle or other sharp object that has been in contact with blood, tissue or other body fluids before the exposure. [1] Even though the acute physiological effects of a needlestick injury are generally negligible, these injuries can lead to transmission of blood-borne diseases ...

  3. Surgical suture - Wikipedia

    en.wikipedia.org/wiki/Surgical_suture

    A surgical suture, also known as a stitch or stitches, is a medical device used to hold body tissues together and approximate wound edges after an injury or surgery. Application generally involves using a needle with an attached length of thread. There are numerous types of suture which differ by needle shape and size as well as thread material ...

  4. Therapeutic index - Wikipedia

    en.wikipedia.org/wiki/Therapeutic_index

    Classically, for clinical indications of an approved drug, TI refers to the ratio of the dose of the drug that causes adverse effects at an incidence/severity not compatible with the targeted indication (e.g. toxic dose in 50% of subjects, TD 50) to the dose that leads to the desired pharmacological effect (e.g. efficacious dose in 50% of ...

  5. Indication (medicine) - Wikipedia

    en.wikipedia.org/wiki/Indication_(medicine)

    Preferred drugs (and other treatments) are also referred to a "first line" or "primary" while others are called "second line", "third line" etc. [7] [8] A drug may be indicated as an "adjunct" or "adjuvant", added to a first line drug. [9] Off-label: Off-label indications are drugs that are used for medical indications that have not been ...

  6. Incyte's $750 Million Escient Deal Faces Setback With ... - AOL

    www.aol.com/incytes-750-million-escient-deal...

    Incyte's $750 Million Escient Deal Faces Setback With Toxicology Issues In Two Investigational Drugs, Analyst Flags Challenges ... as the proof-of-concept data across all three indications was ...

  7. Ventral rectopexy - Wikipedia

    en.wikipedia.org/wiki/Ventral_rectopexy

    When suturing synthetic mesh to the rectum, the use of absorbable sutures leads to lower risk of complications compared to non-resorbable sutures. [5] When mesh erosion into the vagina occurs, a further surgical procedure is required to remove the tissue from the mesh and to close the vaginal wall over the defect. [ 5 ]

  8. Surgery - Wikipedia

    en.wikipedia.org/wiki/Surgery

    Surgery [a] is a medical specialty that uses manual and instrumental techniques to diagnose or treat pathological conditions (e.g., trauma, disease, injury, malignancy), to alter bodily functions (e.g., malabsorption created by bariatric surgery such as gastric bypass), to reconstruct or improve aesthetics and appearance (cosmetic surgery), or to remove unwanted tissues (body fat, glands ...

  9. Diabetes and weight loss drugs shown to reduce alcohol ...

    www.aol.com/diabetes-weight-loss-drugs-shown...

    Ozempic, Wegovy and other GLP-1 drugs have been shown to curb alcoholism, a new study suggests. Researchers explain why diabetes and weight loss drugs work better than alcohol medications.