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Saw palmetto extract has been studied in clinical trials as a possible treatment for people with prostate cancer and for men with lower urinary tract symptoms associated with BPH. [1] [3] As of 2023, there is insufficient scientific evidence that saw palmetto extract is effective for treating cancer or BPH and its symptoms.
A 2015 Cochrane review found that NSAA monotherapy for prostate cancer had a greater risk of treatment discontinuation due to adverse effects than monotherapy with a GnRH agonist or surgical castration (RR = 1.82). [122] This included a greatly increased risk of breast pain (RR = 22.97) and gynecomastia (RR = 8.43). [122]
Saw palmetto (or Serenoa repens) – a type of palm tree found growing in the southeastern United States. Its extract has been promoted as a prostate cancer medicine; however, according to the American Cancer Society, "available scientific studies do not support claims that saw palmetto can prevent or treat prostate cancer in humans". [100]
This is because with continued use of six months to a year, saw palmetto reduces levels of PSA (prostate-specific antigen), an antigen that can indicate prostate cancer when found in high numbers.
How saw palmetto extract may help benefit men by reducing the uncomfortable symptoms of an enlarged prostate, including not being able to urinate easily.
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