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This therapy ties to the Hygiene hypothesis in that the lack of exposure to bacteria and parasites such as helminths can cause a weaker immune system leading to being more susceptible to autoimmune disease. [4] [5] Helminth worms are members of two phyla: nematodes, which are primarily used in human helminthic therapy, and flat worms . [2]
Side effects in humans may include poor coordination, abdominal pain, vomiting, headache, and allergic reactions. [4] While it may be used during pregnancy, it is not recommended for use during breastfeeding. [4] Praziquantel is in the anthelmintic class of medications. [3] It works partly by affecting the function of the worm's sucker. [3]
Pyrantel is a medication used to treat a number of parasitic worm infections. [2] This includes ascariasis, hookworm infections, enterobiasis (pinworm infection), trichostrongyliasis, and trichinellosis. [2] It is taken by mouth. [2] Side effects include nausea, headache, dizziness, trouble sleeping, and rash. [2]
Very rarely Stevens–Johnson syndrome, liver damage, severe allergy has been reported [17] May lower blood sugar excessively in combination with diabetes medication. [17] Contains a chemical linked to possible birth defects. [17]
Anthelmintic resistance in parasites is widespread; drug resistance exists in all livestock hosts and to all anthelmintic drug classes. [13] This is a major threat to the sustainability of modern ruminant livestock production, resulting in reduced productivity, compromised animal health and welfare, [ 12 ] and increased greenhouse gas emissions ...
Side effects are generally few, but can include abdominal pain and headaches. [1] Biliary colic may occur due to dying worms. [2] While no harm has been found with use during pregnancy, triclabendazole has not been studied well in this population. [2] It is a member of the benzimidazole family of medications for worms. [1]
Drenching Merino hoggets, Walcha, NSW U.S. soldiers treating animals with de-worming medication in Eswatini during VETCAP. Deworming (sometimes known as worming, drenching or dehelmintization) is the giving of an anthelmintic drug (a wormer, dewormer, or drench) to a human or animals to rid them of helminths parasites, such as roundworm, flukes and tapeworm.
Parasitic worms influence what kinds of T helper cells are activated. In the past, helminths were thought to simply suppress T-helper Type 1 (Th1) cells while inducing T-helper Type 2 (Th2) cells. [9] Rook points out that this hypothesis would only explain the regulatory effects of parasitic worms on autoimmune diseases caused by Th1 cells. [10]
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