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[1] [2] It contains the three antibiotics neomycin, polymyxin B, and bacitracin. [1] It is for topical use. [3] [4] Possible side effects include itchiness and skin rash, [5] and in rare cases hearing loss. [5] It is relatively broad spectrum, being effective against both Gram-negative and Gram-positive bacteria. [2]
Acute paronychia is usually caused by bacteria. It is often treated with antibiotics, either topical (applied to the skin) or oral (taken by mouth), or both.Chronic paronychia is most often caused by a yeast infection of the soft tissues around the nail but can also be traced to a bacterial infection.
Combination creams are best avoided to improve treatment outcomes, reduce the possibility of skin atrophy associated with prolonged topical glucocorticoid use, and limit the cost of treatment. It can be effective in treating chronic paronychia. The preferred treatment of tinea infections is therefore clotrimazole monotherapy. [11]
Bacitracin is a narrow-spectrum antibiotic. It targets Gram-positive bacteria, especially those that cause skin infections. The following represents susceptibility data for a few medically significant microorganisms. [9] Staphylococcus aureus – ≤0.03 μg/mL – 700 μg/mL; Staphylococcus epidermidis – 0.25 μg/mL – >16 μg/mL
Mupirocin, sold under the brand name Bactroban among others, is a topical antibiotic useful against superficial skin infections such as impetigo or folliculitis. [5] [6] [7] It may also be used to get rid of methicillin-resistant S. aureus (MRSA) when present in the nose without symptoms. [6]
Nitrofurazone was previously available as a prescription in the U.S., and was indicated as a topical solution, topical cream, or topical ointment for the treatment of bacterial skin infections, wounds, burns, and ulcers. [2] It was also used as a prophylactic measure to prevent infection that could potentially result in skin graft rejection.
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The following is a list of antibiotics. The highest division between antibiotics is bactericidal and bacteriostatic . Bactericidals kill bacteria directly, whereas bacteriostatics prevent them from dividing.