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Poliomyelitis (/ ˌ p oʊ l i oʊ ˌ m aɪ ə ˈ l aɪ t ɪ s / POH-lee-oh-MY-ə-LY-tiss), commonly shortened to polio, is an infectious disease caused by the poliovirus. [1] Approximately 75% of cases are asymptomatic; [5] mild symptoms which can occur include sore throat and fever; in a proportion of cases more severe symptoms develop such as headache, neck stiffness, and paresthesia.
Polio typically spreads from person to person via fecal-oral transmission, according to the CDC, but it can also spread through a sick person’s respiratory droplets. You might catch it from ...
The virus infects the throat and intestines, and can cause flu-like symptoms. Paralysis from the polio virus is rare. This year, polio cases have been detected in New York state, London and Jerusalem.
The protein has several domains of which domain D1 contains the polio virus binding site. Within this domain, 37 amino acids are responsible for binding the virus. Poliovirus is an enterovirus. Infection occurs via the fecal–oral route, meaning that one ingests the virus and viral replication occurs in the gastrointestinal tract. [42]
Preventing polio. The first polio vaccine was developed in the early 1950s by Dr. Jonas Salk and approved for use throughout the US in 1955. It is an injectable, inactivated polio vaccine that is ...
A child receives oral polio vaccine during a 2002 campaign to immunize children in India. Poliovirus. Polio eradication, the goal of permanent global cessation of circulation of the poliovirus and hence elimination of the poliomyelitis (polio) it causes, is the aim of a multinational public health effort begun in 1988, led by the World Health Organization (WHO), the United Nations Children's ...
Post-polio syndrome (PPS, poliomyelitis sequelae) is a group of latent symptoms of poliomyelitis (polio), occurring in more than 80% of polio infections. The symptoms are caused by the damaging effects of the viral infection on the nervous system and typically occur 15 to 30 years after an initial acute paralytic attack.
“The oral polio vaccine is not used in the U.S. because it is live attenuated vaccine, meaning that it exposes the body to a weakened version of the virus leading to an immune response and not ...