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  2. Central nervous system fatigue - Wikipedia

    en.wikipedia.org/wiki/Central_Nervous_System_Fatigue

    Central nervous system fatigue, or central fatigue, is a form of fatigue that is associated with changes in the synaptic concentration of neurotransmitters within the central nervous system (CNS; including the brain and spinal cord) which affects exercise performance and muscle function and cannot be explained by peripheral factors that affect muscle function.

  3. Hypothalamus - Wikipedia

    en.wikipedia.org/wiki/Hypothalamus

    The hypothalamus controls body temperature, hunger, important aspects of parenting and maternal attachment behaviours, thirst, [4] fatigue, sleep, circadian rhythms, and is important in certain social behaviors, such as sexual and aggressive behaviors. [5] [6]

  4. Hypothalamic–pituitary–thyroid axis - Wikipedia

    en.wikipedia.org/wiki/Hypothalamic–pituitary...

    Very few animals (e.g. axolotls and sloths) have impaired thyroid homeostasis that exhibits a very low set-point that is assumed to underlie the metabolic and ontogenetic anomalies of these animals. The pituitary gland secretes thyrotropin (TSH; Thyroid Stimulating Hormone) that stimulates the thyroid to secrete thyroxine (T4) and, to a lesser ...

  5. Muscle fatigue - Wikipedia

    en.wikipedia.org/wiki/Muscle_fatigue

    Muscle fatigue is when muscles that were initially generating a normal amount of force, then experience a declining ability to generate force. It can be a result of vigorous exercise , but abnormal fatigue may be caused by barriers to or interference with the different stages of muscle contraction .

  6. Homeostasis - Wikipedia

    en.wikipedia.org/wiki/Homeostasis

    Thus, to Barcroft homeostasis was not only organized by the brain—homeostasis served the brain. [13] Homeostasis is an almost exclusively biological term, referring to the concepts described by Bernard and Cannon, concerning the constancy of the internal environment in which the cells of the body live and survive.

  7. Fatigue - Wikipedia

    en.wikipedia.org/wiki/Fatigue

    Fatigue in a medical context is used to cover experiences of low energy that are not caused by normal life. [2] [3]A 2021 review proposed a definition for fatigue as a starting point for discussion: "A multi-dimensional phenomenon in which the biophysiological, cognitive, motivational and emotional state of the body is affected resulting in significant impairment of the individual's ability to ...

  8. Stress (biology) - Wikipedia

    en.wikipedia.org/wiki/Stress_(biology)

    Physiological stress represents a wide range of physical responses that occur as a direct effect of a stressor causing an upset in the homeostasis of the body. Upon immediate disruption of either psychological or physical equilibrium the body responds by stimulating the nervous, endocrine, and immune systems. The reaction of these systems ...

  9. Synaptic fatigue - Wikipedia

    en.wikipedia.org/wiki/Synaptic_fatigue

    Short-term synaptic depression can affect many synapses of many different types of neurons. [5] The existence and observations of synaptic fatigue are accepted universally, although the exact mechanisms underlying the phenomenon are not completely understood. It is generally seen in mature cells at high frequencies of stimuli (>1 Hz).