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Chronic fatigue syndrome (CFS) requires the additional symptoms of: post-exertional malaise (significantly worsening symptoms with activity which results in a significant reduction in daily activities, which may be delayed by up to 3 days) sleep dysfunction; either: cognitive problems, or; orthostatic intolerance.
Malaise is a non-specific symptom and can be present in the slightest ailment, such as an emotion (causing fainting, a vasovagal response) or hunger (light hypoglycemia [2]), to the most serious conditions (cancer, stroke, heart attack, internal bleeding, etc.).
Fatigue is a state of tiredness (which is not sleepiness), exhaustion [1] or loss of energy. [2] [3]Fatigue (in the medical sense) is sometimes associated with medical conditions including autoimmune disease, organ failure, chronic pain conditions, mood disorders, heart disease, infectious diseases, and post-infectious-disease states. [4]
The symptoms include many of the symptoms associated with milder degrees of hypoglycemia, especially the adrenergic symptoms, but do not progress to objective impairment of brain function, seizures, coma, or brain damage. [citation needed] Shakiness; Sense of weakness; Altered or depressed mood; Confusion; Fatigue; Anxiety; Paleness; Perspiration
In the elderly, hypoglycemia can produce focal stroke-like effects or a hard-to-define malaise. [medical citation needed] The symptoms of a single person do tend to be similar from episode to episode. In the large majority of cases, hypoglycemia severe enough to cause seizures or unconsciousness can be reversed without obvious harm to the brain.
Post-exertional malaise (PEM), sometimes referred to as post-exertional symptom exacerbation (PESE) [1] or post-exertional neuroimmune exhaustion (PENE), [2] is a worsening of symptoms that occurs after minimal exertion. It is the hallmark symptom of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and common in long COVID and ...
Weakness is a symptom of many different medical conditions. [1] The causes are many and can be divided into conditions that have true or perceived muscle weakness. True muscle weakness is a primary symptom of a variety of skeletal muscle diseases, including muscular dystrophy and inflammatory myopathy .
Frailty is a complex condition that is a result of multiple body systems experiencing decline in function, and the more body systems that are affected, the higher the risk is for developing frailty. There is a variety of risk factors and signs that can suggest an older person having frailty. However, the development of any of these risk factors ...
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