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Fundic gland polyposis is a medical syndrome where the fundus and the body of the stomach develop many fundic gland polyps.The condition has been described both in patients with familial adenomatous polyposis (FAP) and attenuated variants (AFAP), and in patients in whom it occurs sporadically.
A fundic gland polyp is a type of polyp, found in the fundus of the stomach. Fundic gland polyps are found in 0.8 to 1.9% of patients who undergo esophagogastroduodenoscopy, and are more common in middle-aged women. [2] The risk of malignancy is very low or none, when sporadic. [3]
Prophylactic colectomy is indicated if more than a hundred polyps are present, if there are severely dysplastic polyps, or if multiple polyps larger than 1 cm are present. Treatment for the two milder forms of FAP may be substantially different from the more usual variant, as the number of polyps is far fewer, allowing more options.
Named lectures include the Sir Arthur Hurst lecture and the Sir Francis Avery Jones BSG Research medallist. Recent presidents have been Hermon Dowling (1996–1997), Chris Hawkey (2010), Jon Rhodes (2011–12), Ian Gilmore (2013–14), Ian Forgacs (2014–16), Martin Lombard (2016–18), Cathryn Edwards (2018–20), Alastair McKinlay (2020-22 ...
[55] [32] H. pylori-induced gastric cancer is the third highest cause of worldwide cancer mortality as of 2018. [56] Because of the usual lack of symptoms, when gastric cancer is finally diagnosed it is often fairly advanced. More than half of gastric cancer patients have lymph node metastasis when they are initially diagnosed. [57]
Food and diet The types of food consumed and diet consumed plays a role in the manifestation of FGID [ 27 ] and also their relationship to intestinal microbiota. [ 28 ] Studies have shown that specific changes in diet (e.g., low FODMAP—fermentable oligo-, di-, and monosaccharides and polyols, or gluten restriction in some patients) may help ...
Recent research has shown that autoimmune metaplastic atrophic gastritis (AMAG) is a result of the immune system attacking the parietal cells. [6]Environmental metaplastic atrophic gastritis (EMAG) is due to environmental factors, such as diet and H. pylori infection.
The countless polyps in the colon predispose to the development of colon cancer; if the colon is not removed, the chance of colon cancer is considered to be very significant. Polyps may also grow in the stomach, duodenum, spleen, kidneys, liver, mesentery, and small bowel. In a small number of cases, polyps have also appeared in the cerebellum.