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Intoxication does have real physiological effects, such as altering a drinker's perception of space and time, reducing psychomotor skills, and disrupting equilibrium. [74] But some effects and the degree of the effects that are attributed to alcohol can be due to the expectations rather than the substance itself, [75] similar to the placebo ...
Alcohol breaks down in the body into a substance called acetaldehyde, which can damage your cells and stop them from repairing themselves. That creates the conditions for cancer to grow.
The initial buzz and immediate effects of alcohol may be familiar. Here’s how the long-term consequences of excessive drinking can gradually take a toll on your health. 1.
Going from hot to cold places can also affect the body, and alcohol doesn't help. "One factor that can play a role is consuming alcohol while in a hot tub, jacuzzi or sauna or drinking outside on ...
Alcohol affects the nutritional state of chronic drinkers. It can decrease food consumption and lead to malabsorption. It can also create imbalances in skeletal muscle mass and cause muscle wasting. Chronic consumption of alcohol can also increase the breakdown of important proteins in the body which can affect gene expression. [157]
[28] [29] The result of these direct effects is a wave of further indirect effects involving a variety of other neurotransmitter and neuropeptide systems. [25] This presents a novel indirect mechanism and suggests that a metabolite, not the ethanol itself, could cause the behavioural or symptomatic effects of alcohol intoxication.
While this process primarily happens in the liver, Lee says that alcohol byproducts like acetate also impact organs like the heart and brain as they travel through the bloodstream.
The excess amount of blood aldehyde produce facial flushing, nausea, rapid heartbeat, and other adverse effects. [26] [27] Presence of these alleles causes rapid conversion of alcohol to acetaldehyde which can be toxic in large amount. So, the East Asians and Africans feel the adverse effects of alcohol early and stop drinking.