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Thyrotoxic myopathy is usually diagnosed by a neurologist who has extensive experience diagnosing neuromuscular disorders. There are many types of neuromuscular disorders that present similar physical symptoms. Extensive clinical tests are performed first to determine if there is a neuromuscular disorder and then to determine which disorder it is.
Thyrotoxic periodic paralysis (TPP) is a rare condition featuring attacks of muscle weakness in the presence of hyperthyroidism (overactivity of the thyroid gland). Hypokalemia (a decreased potassium level in the blood) is usually present during attacks.
In the United States hyperthyroidism affects about 1.2% of the population. [3] Worldwide, hyperthyroidism affects 2.5% of adults. [8] It occurs between two and ten times more often in women. [1] Onset is commonly between 20 and 50 years of age. [2] Overall the disease is more common in those over the age of 60 years. [1]
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AIT type 2 is a form of an immune system response to the cytotoxic properties of amiodarone and results in a destructive thyroiditis (inflammation in the thyroid). [7] [9] This causes pre-existing thyroid hormones to spill out from damaged cells into the circulation and a resultant immunologic reaction. AIT type 2 usually occurs in patients ...
Thyrotoxicosis factitia (alimentary thyrotoxicosis, exogenous thyrotoxicosis) [1] [2] is a condition of thyrotoxicosis caused by the ingestion [3] of exogenous thyroid hormone. [4] [5] It can be the result of mistaken ingestion of excess drugs, such as levothyroxine [6] and triiodothyronine, [7] or as a symptom of Munchausen syndrome.
(G72.0) Drug-induced myopathy Glucocorticoid myopathy is caused by this class of steroids increasing the breakdown of the muscle proteins leading to muscle atrophy. [6] (G72.1) Alcoholic myopathy (G72.2) Myopathy due to other toxic agents - including atypical myopathy in horses caused by toxins in sycamore seeds and seedlings. [7] [8] (M33.0-M33.1)
[8] [49] Subclinical hypothyroidism is estimated to affect approximately 2% of children; in adults, subclinical hypothyroidism is more common in the elderly, and in White people. [48] There is a much higher rate of thyroid disorders, the most common of which is hypothyroidism, in individuals with Down syndrome [ 29 ] [ 61 ] and Turner syndrome .