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  2. Timeline of antibiotics - Wikipedia

    en.wikipedia.org/wiki/Timeline_of_antibiotics

    1942 – gramicidin S, the first peptide antibiotic; 1942 – sulfadimidine; 1943 – sulfamerazine; 1944 – streptomycin, the first aminoglycoside [2] 1947 – sulfadiazine; 1948 – chlortetracycline, the first tetracycline; 1949 – chloramphenicol, the first amphenicol [2] 1949 – neomycin; 1950 – oxytetracycline; 1950 – penicillin G ...

  3. Methicillin - Wikipedia

    en.wikipedia.org/wiki/Methicillin

    Methicillin and other β-lactam antibiotics are structural analogs of D-alanyl-alanine, and the transpeptidase enzymes that bind to them are sometimes called penicillin-binding proteins (PBPs). [3] Methicillin is actually a penicillinase-resistant β-lactam antibiotic. Penicillinase is a bacterial enzyme produced by bacteria resistant to other ...

  4. List of drugs by year of discovery - Wikipedia

    en.wikipedia.org/wiki/List_of_drugs_by_year_of...

    In 1907 Alfred Bertheim synthesized Arsphenamine, the first man-made antibiotic. In 1927 Erik Rotheim patented the first aerosol spray can. In 1933 Robert Pauli Scherer created a method to develop softgels. William Roberts studies about penicillin were continued by Alexander Fleming, who in 1928 concluded that penicillin had an antibiotic ...

  5. History of penicillin - Wikipedia

    en.wikipedia.org/wiki/History_of_penicillin

    The article was translated into Japanese, and production of penicillin was underway by 1 February 1944. By mid-May, a research team under Hamao Umezawa had tested 750 different strains of mould and found that 75 exhibited antibiotic activity. Experiments were conducted on mice to determine efficacy and toxicity.

  6. Drug discovery - Wikipedia

    en.wikipedia.org/wiki/Drug_discovery

    In the fields of medicine, biotechnology, and pharmacology, drug discovery is the process by which new candidate medications are discovered. [1] Historically, drugs were discovered by identifying the active ingredient from traditional remedies or by serendipitous discovery, as with penicillin.

  7. 2 NWTC students found a new antibiotic in soil at ... - AOL

    www.aol.com/2-nwtc-students-found-antibiotic...

    Half of the antibiotics typically used today were found between 1950 and 1960, which was considered the golden age of antibiotic discovery. The last class of antibiotics used as treatment was ...

  8. Penicillin - Wikipedia

    en.wikipedia.org/wiki/Penicillin

    Other named constituents of natural Penicillium, such as penicillin A, were subsequently found not to have antibiotic activity and are not chemically related to antibiotic penicillins. [8] The precise constitution of the penicillin extracted depends on the species of Penicillium mould used and on the nutrient media used to culture the mould. [8]

  9. Streptomyces isolates - Wikipedia

    en.wikipedia.org/wiki/Streptomyces_isolates

    Most clinical antibiotics were found during the "golden age of antibiotics" (1940s–1960s). Actinomycin was the first antibiotic isolated from Streptomyces in 1940, followed by streptomycin three years later. Antibiotics from Streptomyces isolates (including various aminoglycosides) would go on to comprise over two-thirds of all marketed ...