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Dimenhydrinate is an over-the-counter (OTC) first-generation antihistamine indicated for the prevention and relief of nausea and vomiting from a number of causes, including motion-sickness and post-operative nausea. [2] Dimenhydrinate can also be used for Insomnia, but this is an off label use. [5]
Dimenhydrinate (Gravol, Dramamine) Doxylamine (Bonjesta, Unisom) Mirtazapine (Remeron) is an antidepressant that also has antiemetic effects. [5] [6] It is a potent histamine H1 receptor antagonist, K i =1.6 nM, [7] and also exhibits notable 5-HT 3 antagonism. [6] Meclizine (Bonine, Antivert)
It is known to be sedative, making drowsiness a common side effect. It is an oral drug to be taken by mouth, to relieve symptoms of allergy, hay fever and the common cold. [1] It can also be used to relieve allergies such as itching, sneezing, runny nose, rash and hives. [1] Benadryl Allergy tablets. Benadryl Allergy for Children is also available.
The evidence does not report how antihistamines affect women differently than men. [1] Different studies have reported on antihistamine use in children, with various studies finding evidence that certain antihistamines could be used by children 2 years of age, and other drugs being safer for younger or older children. [1]
"Treatment of vertigo due to acute unilateral vestibular loss with a fixed combination of cinnarizine and dimenhydrinate: a double-blind, randomized, parallel-group clinical study". Clin Ther . 26 (6): 866–77.
It is expected that low doses of diphenhydramine taken occasionally will cause no adverse effects in breastfed infants. Large doses and long-term use may affect the baby or reduce breast milk supply, especially when combined with sympathomimetic drugs , such as pseudoephedrine, or before the establishment of lactation.
Democratic Rep. Nancy Pelosi, 84, underwent a successful hip replacement surgery after falling while in Luxembourg with a congressional delegation, her office said Saturday. "Earlier this morning ...
Some common side effects such as drowsiness, dry mouth, and tiredness may occur. Meclizine has been shown to have fewer dry mouth side effects than the traditional treatment for motion sickness, transdermal scopolamine. [16] A very serious allergic reaction to this drug is unlikely, but immediate medical attention should be sought if it occurs.