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Topically applied sodium hyaluronate can facilitate the absorption of biomacromolecules, i.e. pharmaceuticals, and function like a nanocarrier. [16] Its effects on skin depend on the hyaluronate formulation and skin health: In barrier-deficient skin it restricted the delivery of biomacromolecules to the stratum corneum and viable epidermis.
The USP is published in a combined volume with the National Formulary (a formulary) as the USP-NF. [2] If a drug ingredient or drug product has an applicable USP quality standard (in the form of a USP-NF monograph), it must conform in order to use the designation "USP" or "NF".
Sodium hyaluronate, the sodium salt of hyaluronic acid, a glycosaminoglycan found in various human connective tissue. Microbial hyaluronic acid production, the process by which microorganisms are utilized in fermentation to synthesize hyaluronic acid. Alguronic acid, trade name for a mix of polysaccharides produced by microalgae. Inhibits ...
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It also includes an appendix with monographs on organic named reactions. The 15th edition was published in April 2013. Monographs in The Merck Index typically contain: [1] a CAS registry number; synonyms of the substance, such as trivial names and International Union of Pure and Applied Chemistry nomenclature; a chemical formula; molecular weight
Chemical structure of one unit in a chondroitin sulfate chain. Chondroitin-4-sulfate: R 1 = H; R 2 = SO 3 H; R 3 = H. Chondroitin-6-sulfate: R 1 = SO 3 H; R 2, R 3 = H.. Chondroitin sulfate is a sulfated glycosaminoglycan (GAG) [1] composed of a chain of alternating sugars (N-acetylgalactosamine and glucuronic acid).
Four different purified hyaluronidases have been approved for use in the United States, three of animal origin and one recombinant. They are indicated as adjuvants in subcutaneous fluid administration for achieving hydration, for increasing the dispersion and absorption of other injected drugs, or for improving resorption of radiopaque agents, in subcutaneous urography.
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