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Aldosterone stimulates Na + and water reabsorption from the gut, salivary and sweat glands in exchange for K +. Aldosterone stimulates secretion of H + via the H+/ATPase in the intercalated cells of the cortical collecting tubules; Aldosterone upregulates expression of NCC in the distal convoluted tubule chronically and its activity acutely. [18]
The enzyme aldosterone synthase (also known as CYP11B2) acts in this location [3] [4] The expression of neuron-specific proteins in the zona glomerulosa cells of human adrenocortical tissues has been predicted and reported by several authors [5] [6] [7] and it was suggested that the expression of proteins like the neuronal cell adhesion ...
The hormone receptor without ligand binding interacts with heat shock proteins and prevents the transcription of targeted genes. Aldosterone and cortisol (a glucosteroid) have similar affinity for the mineralocorticoid receptor; however, glucocorticoids circulate at roughly 100 times the level of mineralocorticoids. An enzyme exists in ...
The outermost layer, the zona glomerulosa is the main site for the production of aldosterone, a mineralocorticoid. The synthesis and secretion of aldosterone are mainly regulated by the renin–angiotensin–aldosterone system. The zona glomerulosa cells express a specific enzyme aldosterone synthase (also known as CYP11B2).
Glucocorticoids produced in the adrenal cortex were once thought to be responsible for the differentiation of chromaffin cells. More recent research suggests that BMP-4 secreted in adrenal tissue is the main responsible for this, and that glucocorticoids only play a role in the subsequent development of the cells.
James Harden moved into second place on the NBA's career 3-point list and had 20 points and 11 assists to help the Los Angeles Clippers beat the Utah Jazz 116-105 on Sunday night to end a three ...
nearly every cell in the body increased metabolism 5 Thyroxine: T 4: Amino acid derivative thyroid gland: Thyroid follicular cell / Tyrosine: thyroid hormone receptor: nearly every cell in the body Control carbohydrate, protein and fat metabolism and control physical, mental growth of body 6 Dopamine: DA Amino acid derivative substantia nigra ...
Two people are dead after a plane crashed into a building near the Daniel K. Inouye International Airport in Honolulu, according to reports. At around 3:15 p.m. local time on Tuesday, Kamaka Air ...