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Testosterone cypionate, sold under the brand name Depo-Testosterone among others, is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of low testosterone levels in men, [2] [3] [4] including hormone therapy for transgender men.
Testosterone can be taken by a variety of different routes of administration. [2] [3] These include oral, buccal, sublingual, intranasal, transdermal (gels, creams, patches, solutions), vaginal (creams, gels, suppositories), rectal (suppositories), by intramuscular or subcutaneous injection (in oil solutions or aqueous suspensions), and as a subcutaneous implant.
Testosterone is a steroid hormone from the androstane class containing a ketone and a hydroxyl group at positions three and seventeen respectively. It is biosynthesized in several steps from cholesterol and is converted in the liver to inactive metabolites. [8] It exerts its action through binding to and activation of the androgen receptor. [8]
Testosterone esters were synthesized for the first time in 1936, and were found to have greatly improved potency relative to testosterone. [12] Among the esters synthesized, testosterone propionate was the most potent, and for this reason, was selected for further development, subsequently being marketed. [ 12 ]
Testosterone cypionate and testosterone enanthate were formerly available in combination with estradiol cypionate and estradiol valerate, respectively, under the brand names Depo-Testadiol and Ditate-DS, respectively, as oil solutions for intramuscular injection, but these formulations have been discontinued.
Recently, the subject of using testosterone as another way of managing symptoms, such as loss as sex drive, has come back into the news, as actress Kate Winslet has sung the hormone's praises.
Testosterone cypionate: Depo-Testosterone: Oil solution: 50–250 mg 1x/1–4 weeks Testosterone isobutyrate: Agovirin Depot: Aqueous suspension: 50–100 mg 1x/1–2 weeks Testosterone phenylacetate b: Perandren, Androject: Oil solution: 50–200 mg 1×/3–5 weeks Mixed testosterone esters: Sustanon 100, Sustanon 250: Oil solution: 50–250 ...
Testosterone propionate/testosterone cypionate/prasterone (TP/TC/DHEA), sold under the brand name Sten, is an injectable combination medication of testosterone propionate (TP), a fast-acting androgen/anabolic steroid, testosterone cypionate (TC), a long-acting androgen/anabolic steroid, and prasterone (dehydroepiandrosterone; DHEA), an androgen and neurosteroid, which has been used to treat ...
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