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  2. Warfarin - Wikipedia

    en.wikipedia.org/wiki/Warfarin

    The LD 50 for warfarin is 50–100 mg/kg for a single dose, after 5–7 days. [109] LD 50 1 mg/kg for repeated daily doses for 5 days, after 5–8 days. [109] The IDLH value is 100 mg/m 3 (warfarin; various species). [111] Resistance to warfarin as a poison has developed in many rat populations due to an autosomal dominant on chromosome 1 in ...

  3. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    The monitoring of warfarin and keeping the international normalized ratio (INR) between 2.0 and 3.0, along with avoiding over and under treatment, has driven a search for an alternative. [3] [14] A naturally occurring inhibitor of factor Xa was reported in 1971 by Spellman et al. from the dog hookworm. [15]

  4. Warfarin necrosis - Wikipedia

    en.wikipedia.org/wiki/Warfarin_necrosis

    Warfarin necrosis is a rare but severe complication of treatment with warfarin or related anticoagulants. [2] The typical patient appears to be an obese, middle aged woman (median age 54 years, male to female ratio 1:3). [1] [3]: 122–3 This drug eruption usually occurs between the third and tenth days of therapy with warfarin derivatives. [1]

  5. Deep vein thrombosis - Wikipedia

    en.wikipedia.org/wiki/Deep_vein_thrombosis

    For around 50 years, a months-long warfarin (Coumadin) regimen was the mainstay of pharmacological treatment. [194] [195] To avoid the blood monitoring required with warfarin and the injections required by heparin and heparin-like medicines, direct oral anticoagulants (DOACs) were developed. [195]

  6. Brodifacoum - Wikipedia

    en.wikipedia.org/wiki/Brodifacoum

    Brodifacoum is a 4-hydroxycoumarin anticoagulant, with a similar mode of action to its historical predecessors dicoumarol and warfarin.However, due to very high potency and long duration of action (elimination half-life of 20 – 130 days), it is characterised as a "second-generation" or "superwarfarin" anticoagulant.

  7. Today's Wordle Hint, Answer for #1257 on Wednesday, November ...

    www.aol.com/todays-wordle-hint-answer-1257...

    Today's Wordle Answer for #1257 on Wednesday, November 27, 2024. Today's Wordle answer on Wednesday, November 27, 2024, is SLANG. How'd you do? Next: Catch up on other Wordle answers from this week.

  8. Former ‘Baywatch’ Star Nicole Eggert Gives Update on Breast ...

    www.aol.com/former-baywatch-star-nicole-eggert...

    Baywatch star Nicole Eggert shared a health update regarding her year-long (and counting) journey with breast cancer. In December 2023, Eggert was told she had stage 2 of a rare, slow-growing form ...

  9. Robert Kraft reportedly denied entry into Pro Football Hall ...

    www.aol.com/sports/robert-kraft-reportedly...

    Robert Kraft will have to wait at least another year to reach the Pro Football Hall of Fame. The New England Patriots owner, who has made a concerted push in recent years to be enshrined in Canton ...

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