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  2. Prophase - Wikipedia

    en.wikipedia.org/wiki/Prophase

    Prophase is the first step of cell division in mitosis. As it occurs after G2 of interphase, DNA has been already replicated when prophase begins. [1] Fluorescence microscope image of two mouse cell nuclei in prophase (scale bar is 5 μm).

  3. Mitosis - Wikipedia

    en.wikipedia.org/wiki/Mitosis

    In this stage, chromosomes are long, thin, and thread-like. Each chromosome has two chromatids. The two chromatids are joined at the centromere. Gene transcription ceases during prophase and does not resume until late anaphase to early G 1 phase. [40] [41] [42] The nucleolus also disappears during early prophase. [43]

  4. Chromosome segregation - Wikipedia

    en.wikipedia.org/wiki/Chromosome_segregation

    Chromosome segregation is the process in eukaryotes by which two sister chromatids formed as a consequence of DNA replication, or paired homologous chromosomes, separate from each other and migrate to opposite poles of the nucleus. This segregation process occurs during both mitosis and meiosis. Chromosome segregation also occurs in prokaryotes ...

  5. Cell division - Wikipedia

    en.wikipedia.org/wiki/Cell_division

    The thick lines are chromosomes, and the thin blue lines are fibers pulling on the chromosomes and pushing the ends of the cell apart. The cell cycle in eukaryotes: I = Interphase, M = Mitosis, G 0 = Gap 0, G 1 = Gap 1, G 2 = Gap 2, S = Synthesis, G 3 = Gap 3. Cell division is the process by which a parent cell divides into two daughter cells. [1]

  6. Spindle checkpoint - Wikipedia

    en.wikipedia.org/wiki/Spindle_checkpoint

    Using different types of genetic studies, it has been established that diverse kinds of defects are able to activate the SAC: spindle depolymerization, [8] [9] the presence of dicentric chromosomes (with two centromeres), [10] centromeres segregating in an aberrant way, [11] defects in the spindle pole bodies in S. cerevisiae, [12] defects in ...

  7. Replication timing - Wikipedia

    en.wikipedia.org/wiki/Replication_timing

    [11] [12] In all multi-cellular organisms where it has been measured, early replication takes place in the interior of the nucleus and the chromatin around the periphery is replicated later. Recently developed methods to measure the points where different parts of chromosomes touch each other are almost perfectly aligned to when they replicate. [3]

  8. Cleavage furrow - Wikipedia

    en.wikipedia.org/wiki/Cleavage_furrow

    Prophase is the initial phase when spindle fibers appear that function to move the chromosomes toward opposite poles. This spindle apparatus consists of microtubules, microfilaments and a complex network of various proteins. During metaphase, the chromosomes line up using the spindle apparatus in the middle of the cell along the equatorial plate.

  9. PMAT - Wikipedia

    en.wikipedia.org/wiki/PMAT

    Four phases of mitosis: prophase, metaphase, anaphase, and telophase: Prophase: Chromatin into chromosomes, the nuclear envelope breaks down, chromosomes attach to spindle fibers by their centromeres. Metaphase: Chromosomes line up along the metaphase plate (center of the cell). Anaphase: Sister chromatids are pulled to opposite poles of the cell.