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Atoms in the heavy chain are colored red on the left-hand side, and atoms in the light chains are colored orange and yellow. A myosin light chain is a light chain (small polypeptide subunit) of myosin . [ 1 ]
In smooth muscle, a single gene [20]) codes for the heavy chains myosin II, but splice variants of this gene result in four distinct isoforms. [19] It also contains 4 myosin light chains (MLC), resulting in 2 per head, weighing 20 (MLC 20) and 17 (MLC 17) kDa. [19] These bind the heavy chains in the "neck" region between the head and tail.
Myosin light chain 6B is a protein that in humans is encoded by the MYL6B gene. [5] [6] [7] Myosin is a hexameric ATPase cellular motor protein.It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains.
Smooth muscle tissue is mostly made of actin and myosin, [3] two proteins that interact together to produce muscle contraction and relaxation. Myosin II, also known as conventional myosin, has two heavy chains that consist of the head and tail domains and four light chains (two per head) that bind to the heavy chains in the “neck” region.
Light meromyosin has a long, straight portion in the “tail” region. Heavy meromyosin (HMM) is a protein chain terminating in a globular head portion/cross bridge. [3] HMM consists of two subunits, Heavy Meromyosin Subunit 1 and 2 (HMMS-1 and HMMS-2). The majority of myosin activity is concentrated in HMMS-1.
n/a Ensembl ENSG00000215375 n/a UniProt Q02045 n/a RefSeq (mRNA) NM_002477 NM_001363650 n/a RefSeq (protein) NP_002468 NP_001350579 n/a Location (UCSC) Chr 4: 0.67 – 0.68 Mb n/a PubMed search n/a Wikidata View/Edit Human Myosin light chain 5 is a protein that, in humans, is encoded by the MYL5 gene. Function This gene encodes one of the myosin light chains, a component of the hexameric ...
Myosin light chain 3, skeletal muscle isoform is a protein that in humans is encoded by the MYL1 gene. [5] [6] [7]Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains.
Myosin light polypeptide 6 is a protein that in humans is encoded by the MYL6 gene. [5] [6] [7] [8]Myosin is a hexameric ATPase cellular motor protein.It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains.