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Timing is important to wound healing. Critically, the timing of wound re-epithelialization can decide the outcome of the healing. [11] If the epithelization of tissue over a denuded area is slow, a scar will form over many weeks, or months; [12] [13] If the epithelization of a wounded area is fast, the healing will result in regeneration.
In a major injury, if epithelial cell migration and tissue contraction cannot cover the wound, suturing the edges of the injured skin together, or even replacement of lost skin with skin grafts, may be required to restore the skin. As epithelial cells continue to migrate around the scab, the dermis is repaired by the activity of stem cells.
Most injuries to the skin are minor and do not require specialist treatment. Lacerations of the skin are typically repaired with sutures, staples, or adhesives. The skin is susceptible to burns, and burns to the skin often cause blistering. Abrasive trauma scrapes or rubs off the skin, and severe abrasions require skin grafting to repair. Skin ...
These cells are then capable of speeding wound repair by contracting the edges of the wound. Early work on wound healing showed that granulation tissue taken from a wound could contract in vitro (or in an organ bath) in a similar fashion to smooth muscle, when exposed to substances that cause smooth muscle to contract, such as adrenaline or ...
Flap surgery is a technique essential to plastic and reconstructive surgery.A flap is defined as tissue that can be moved to another site and has its own blood supply.This is in comparison to a skin graft which does not have its own blood supply and relies on vascularization from the recipient site. [2]
Abrasions on elbow and lower arm. The elbow wound will produce a permanent scar. A first-degree abrasion involves only epidermal injury. A second-degree abrasion involves the epidermis as well as the dermis and may bleed slightly. A third-degree abrasion involves damage to the subcutaneous layer and the skin and is often called an avulsion.
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Scars result from the biological process of wound repair in the skin, as well as in other organs, and tissues of the body. Thus, scarring is a natural part of the healing process. With the exception of very minor lesions, every wound (e.g., after accident, disease, or surgery) results in some degree of scarring.