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Most esters of these corticosteroids are not included in this list; for esters, see here instead. The most common structural modifications in synthetic corticosteroids include 1(2)-dehydrogenation, 6α-, 9α-, 16α-, and 16β-substitution (with a halogen or methyl group), 16α,17α-acetonidation, and 17α- and 21-esterification.
Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones.Two main classes of corticosteroids, glucocorticoids and mineralocorticoids, are involved in a wide range of physiological processes, including stress response, immune response, and regulation of inflammation, carbohydrate metabolism ...
Methylprednisolone (Depo-Medrol, Medrol, Solu-Medrol) is a synthetic glucocorticoid, primarily prescribed for its anti-inflammatory and immunosuppressive effects. [4] [5] [6] It is either used at low doses for chronic illnesses or used concomitantly at high doses during acute flares.
Betamethasone is a steroid medication. [3] It is used for a number of diseases including rheumatic disorders such as rheumatoid arthritis and systemic lupus erythematosus, skin diseases such as dermatitis and psoriasis, allergic conditions such as asthma and angioedema, preterm labor to speed the development of the baby's lungs, Crohn's disease, cancers such as leukemia, and along with ...
Budesonide, sold under the brand name Pulmicort, among others, is a steroid medication. [8] It is available as an inhaler , nebulization solution , pill , nasal spray , and rectal forms . [ 8 ] [ 9 ] The inhaled form is used in the long-term management of asthma and chronic obstructive pulmonary disease (COPD).
Topical hydrocortisone is a drug under the class of corticosteroids, which is used for the treatment of skin inflammation, itchiness and allergies. [10] Some examples include insect bites, dermatitis and rash. [11] [12] [13]
Fludrocortisone, sold under the brand name Florinef, among others, is a corticosteroid used to treat adrenogenital syndrome, postural hypotension, and adrenal insufficiency. [ 1 ] [ 2 ] [ 3 ] In adrenal insufficiency, it is generally taken together with hydrocortisone . [ 3 ]
Prednisolone is a corticosteroid drug with predominant glucocorticoid and low mineralocorticoid activity, making it useful for the treatment of a wide range of inflammatory and autoimmune conditions [17] such as asthma, [18] uveitis, pyoderma gangrenosum, rheumatoid arthritis, urticaria, [19] angioedema, [19] ulcerative colitis, pericarditis ...
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