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Lorcaserin, marketed under the brand name Belviq, [4] [5] was a weight-loss drug developed by Arena Pharmaceuticals. It reduces appetite by activating serotonin receptor the 5-HT 2C receptor in the hypothalamus , a region of the brain which is known to control appetite. [ 6 ]
Lorcaserin is approved for use in adults with a body mass index (BMI) of 30 or greater, which is considered obese, or adults with a BMI of 27 or greater and who have at least one weight-related health condition, such as high blood pressure, type 2 diabetes, or high cholesterol. However, sales of Belviq were disappointing.
A European Category 1 Licence is required to purchase phenylpropanolamine for academic use. In the United States, the Food and Drug Administration (FDA) issued a public health advisory [70] against the use of the drug in November 2000. In this advisory, the FDA requested but did not require that all drug companies discontinue marketing products ...
These are the best Cyber Monday deals under $100: Walmart, Amazon, Target, Best Buy, and more. Kate Tully Ellsworth. December 2, 2024 at 6:00 AM.
When you buy a bottle of vitamins from a nutrition store, you’ll probably notice a best-by date on the bottom of the jar. But that inscribed number isn’t a hard-and-fast rule—there is some ...
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Lorcaserin (Belviq) was FDA approved for weight loss but was withdrawn from the market because a safety clinical trial shows an increased occurrence of cancer. [ 11 ] Cannabinoid receptor antagonists were developed to treat obesity because researchers noticed that cannabinoid agonists (such as THC , the main pharmacologically active component ...
Lorcaserin is a very potent agonist, but the potency is dependent on the presence of a chloro substituent in position 8. [ 7 ] [ 33 ] [ 34 ] Arylpiperazine-containing compounds such as mCPP (Figure 7), show good potency toward the 5-HT 2C receptors, but do not have sufficient selectivity for the 5-HT 2C receptors over the other two receptor ...
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109 S High St #100, Columbus, OH · Directions · (614) 224-4261