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  2. Lorcaserin - Wikipedia

    en.wikipedia.org/wiki/Lorcaserin

    Lorcaserin, marketed under the brand name Belviq, [4] [5] was a weight-loss drug developed by Arena Pharmaceuticals. It reduces appetite by activating serotonin receptor the 5-HT 2C receptor in the hypothalamus , a region of the brain which is known to control appetite. [ 6 ]

  3. Arena Pharmaceuticals - Wikipedia

    en.wikipedia.org/wiki/Arena_Pharmaceuticals

    Lorcaserin is approved for use in adults with a body mass index (BMI) of 30 or greater, which is considered obese, or adults with a BMI of 27 or greater and who have at least one weight-related health condition, such as high blood pressure, type 2 diabetes, or high cholesterol. However, sales of Belviq were disappointing.

  4. Phenylpropanolamine - Wikipedia

    en.wikipedia.org/wiki/Phenylpropanolamine

    A European Category 1 Licence is required to purchase phenylpropanolamine for academic use. In the United States, the Food and Drug Administration (FDA) issued a public health advisory [70] against the use of the drug in November 2000. In this advisory, the FDA requested but did not require that all drug companies discontinue marketing products ...

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    These are the best Cyber Monday deals under $100: Walmart, Amazon, Target, Best Buy, and more. Kate Tully Ellsworth. December 2, 2024 at 6:00 AM.

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    When you buy a bottle of vitamins from a nutrition store, you’ll probably notice a best-by date on the bottom of the jar. But that inscribed number isn’t a hard-and-fast rule—there is some ...

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  8. Anti-obesity medication - Wikipedia

    en.wikipedia.org/wiki/Anti-obesity_medication

    Lorcaserin (Belviq) was FDA approved for weight loss but was withdrawn from the market because a safety clinical trial shows an increased occurrence of cancer. [ 11 ] Cannabinoid receptor antagonists were developed to treat obesity because researchers noticed that cannabinoid agonists (such as THC , the main pharmacologically active component ...

  9. 5-HT2C receptor agonist - Wikipedia

    en.wikipedia.org/wiki/5-HT2c_receptor_agonist

    Lorcaserin is a very potent agonist, but the potency is dependent on the presence of a chloro substituent in position 8. [ 7 ] [ 33 ] [ 34 ] Arylpiperazine-containing compounds such as mCPP (Figure 7), show good potency toward the 5-HT 2C receptors, but do not have sufficient selectivity for the 5-HT 2C receptors over the other two receptor ...

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