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  2. Leuprorelin - Wikipedia

    en.wikipedia.org/wiki/Leuprorelin

    Lupron injection was approved by the FDA for treatment of advanced prostate cancer on 9 April 1985. [45] [4] [43] [44] Lupron depot for monthly intramuscular injection was approved by the FDA for palliative treatment of advanced prostate cancer on 26 January 1989. [8]

  3. Side effects of cyproterone acetate - Wikipedia

    en.wikipedia.org/wiki/Side_effects_of_cyprotero...

    The side effects of cyproterone acetate (CPA), a steroidal antiandrogen and progestin, including its frequent and rare side effects, have been studied and characterized.It is generally well-tolerated and has a mild side-effect profile, regardless of dosage, when it used as a progestin or antiandrogen in combination with an estrogen such as ethinylestradiol or estradiol valerate in women.

  4. Cyproterone acetate - Wikipedia

    en.wikipedia.org/wiki/Cyproterone_acetate

    Cyproterone acetate (CPA), sold alone under the brand name Androcur or with ethinylestradiol under the brand names Diane or Diane-35 among others, is an antiandrogen and progestin medication used in the treatment of androgen-dependent conditions such as acne, excessive body hair growth, early puberty, and prostate cancer, as a component of feminizing hormone therapy for transgender individuals ...

  5. Gonadotropin-releasing hormone agonist - Wikipedia

    en.wikipedia.org/wiki/Gonadotropin-releasing...

    A gonadotropin-releasing hormone agonist (GnRH agonist) is a type of medication which affects gonadotropins and sex hormones. [1] They are used for a variety of indications including in fertility medicine and to lower sex hormone levels in the treatment of hormone-sensitive cancers such as prostate cancer and breast cancer, certain gynecological disorders like heavy periods and endometriosis ...

  6. TAP Pharmaceuticals - Wikipedia

    en.wikipedia.org/wiki/TAP_Pharmaceuticals

    Abbott and Takeda agreed to end the partnership in 2008, with Abbott keeping the rights to leuprorelin, which had sales in 2007 of $600 million and a patent expiring in 2015 and the approximately 300 employees who worked on the product, and Takeda keeping the rights to lansoprazole, which had sales of $2.3 billion in 2007 but was facing ...

  7. Bicalutamide - Wikipedia

    en.wikipedia.org/wiki/Bicalutamide

    [18] [27] Hepatic changes that have necessitated discontinuation of bicalutamide, such as marked increases in liver enzymes or hepatitis, have occurred in 0.3 to 1.5% of men in clinical trials, or approximately 1% overall. [27] [13] [33] [122] [123] Elevated liver enzymes with bicalutamide usually occur within the first 3 to 6 months of treatment.

  8. Gonadotropin-releasing hormone antagonist - Wikipedia

    en.wikipedia.org/wiki/Gonadotropin-releasing...

    Doses were 240 then 80 mg/month and 7.5 mg/month, respectively. [ 26 ] Testosterone levels in the long-term androgen deprivation therapy of men with prostate cancer by different GnRH agonists administered at 3 month intervals (goserelin, triptorelin and leuprorelin).

  9. Triptorelin - Wikipedia

    en.wikipedia.org/wiki/Triptorelin

    [3] [4] It is a decapeptide (pGlu-His-Trp-Ser-Tyr- D -Trp-Leu-Arg-Pro-Gly-NH 2 ) and a gonadotropin-releasing hormone agonist (GnRH agonist) used as the acetate or pamoate salts . Primary indications include endometriosis , [ 5 ] for the reduction of uterine fibroids , to treat prostate cancer , and to treat male hypersexuality with severe ...

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