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Secondary muscle fibers then form around the primary fibers near the time of innervation. These muscle fibers form from secondary myoblasts and usually develop as fast muscle fibers. Finally, the muscle fibers that form later arise from satellite cells. [4] Two genes significant in muscle fusion are Mef2 and the twist transcription factor.
Linear growth is a complex process regulated by the growth hormone (GH) – insulin-like growth factor-1 axis, the thyroxine/triiodothyronine axis, androgens, estrogens, vitamin D, glucocorticoids and possibly leptin. [25] GH is secreted by the anterior pituitary gland in response to hypothalamic, pituitary and circulating factors.
In the early development of vertebrate embryos, growth and formation of muscle happens in successive waves or phases of myogenesis. The myosin heavy chain isotype is a major determinant of the specific fiber type. In zebrafish embryos, the first muscle fibers to form are the slow twitch fibers. These cells will undergo migration from their ...
Muscle is a soft tissue, one of the four basic types of animal tissue. Muscle tissue gives skeletal muscles the ability to contract. Muscle is formed during embryonic development, in a process known as myogenesis. Muscle tissue contains special contractile proteins called actin and myosin which interact to cause movement.
Twisting along the body axis by a left-handed chirality is found in all chordates (including vertebrates) and is addressed by the axial twist theory. [28] Growth in embryos is mostly autonomous. [29] For each territory of cells the growth rate is controlled by the combination of genes that are active.
Limb development in vertebrates is an area of active research in both developmental and evolutionary biology, with much of the latter work focused on the transition from fin to limb. [ 1 ] Limb formation begins in the morphogenetic limb field , as mesenchymal cells from the lateral plate mesoderm proliferate to the point that they cause the ...
In humans, the MSTN gene is located on the long (q) arm of chromosome 2 at position 32.2. [5] Myostatin (also known as growth differentiation factor 8, abbreviated GDF8) is a protein that in humans is encoded by the MSTN gene. [6] Myostatin is a myokine that is produced and released by myocytes and acts on muscle cells to inhibit muscle growth. [7]
The body contains three types of muscle tissue: (a) skeletal muscle, (b) smooth muscle, and (c) cardiac muscle. On the anterior and posterior views of the muscular system above, superficial muscles (those at the surface) are shown on the right side of the body while deep muscles (those underneath the superficial muscles) are shown on the left ...