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Calcium carbonate antacid tablets. An antacid is a substance which neutralizes stomach acidity and is used to relieve heartburn, indigestion, or an upset stomach. [1] Some antacids have been used in the treatment of constipation and diarrhea. [2] Marketed antacids contain salts of aluminum, calcium, magnesium, or sodium. [2]
Proton-pump inhibitors have largely superseded the H 2-receptor antagonists, a group of medications with similar effects but a different mode of action, and heavy use of antacids. [3] A potassium-competitive acid blocker (PCAB) revaprazan was marketed in Korea as an alternative to a PPI.
Common side effects include headache, abdominal pain, diarrhea or constipation, and dizziness. [4] Serious side effects may include pneumonia and seizures. [4] [5] Use in pregnancy appears safe but has not been well studied, while use during breastfeeding is not recommended. [1] Famotidine was patented in 1979 and came into medical use in 1985. [6]
1 Adverse effects. 2 References. Toggle the table of contents. Almagate. ... is an aluminium- and magnesium-containing antacid. It was first described in 1984. [1] [2 ...
Antacids would increase the pH environment in the stomach and cause premature release of enteric coated drugs, which are designed to be protected from an acidic environment in stomach. [19] For example, proton-pump inhibitors (PPIs) are enteric coated to protect them from decomposition under an acidic environment. [ 20 ]
Bromo-Seltzer newspaper ad (1908) Emerson Drug Company's Bromo-Seltzer Tower headquarters in Baltimore A horse-drawn Bromo-Seltzer wagon Bromo-Seltzer is a brand of antacid formulated to relieve pain occurring together with heartburn, upset stomach, or acid indigestion.
Eno was first marketed by James Crossley Eno (1827–1915). [4] Legend has it that his idea for the product arose while he was working at the pharmacy of an infirmary in Newcastle, Britain, with Dennis Embleton; Embleton often prescribed an effervescent drink made by mixing sodium bicarbonate and citric acid in water, and Eno adopted this beverage. [5]
Cimetidine, sold under the brand name Tagamet among others, is a histamine H 2 receptor antagonist that inhibits stomach acid production. [1] [9] [10] It is mainly used in the treatment of heartburn and peptic ulcers.
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