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2. Stem cell transplantation for articular cartilage repair

   en.wikipedia.org/wiki/Stem_cell_transplantation...

   The most commonly used source of MSC's is bone marrow aspirate. Most of the adult bone marrow consists of blood cells in various stages of differentiation. [10] These marrow components can be divided into plasma, red blood cells, platelets, and nucleated cells. The adult stem cell fraction is present in the nucleated cells of the marrow.

3. Knee cartilage replacement therapy - Wikipedia

   en.wikipedia.org/wiki/Knee_cartilage_replacement...

   Autologous matrix-induced chondrogenesis, which is also known as AMIC, is a biological treatment option for articular cartilage damage bone marrow stimulating technique in combination with a collagen membrane. It is based on the microfracture surgery with the application of a bi-layer collagen I/III membrane.

4. Articular cartilage repair - Wikipedia

   en.wikipedia.org/wiki/Articular_cartilage_repair

   In particular, mesenchymal stem cells have been shown in animal models to regenerate cartilage. Recently, there has been a published case report of decrease in knee pain in a single individual using autologous mesenchymal stem cells. An advantage to this approach is that a person's own stem cells are used, avoiding transmission of genetic diseases.

5. Articular cartilage stem cell paste grafting - Wikipedia

   en.wikipedia.org/wiki/Articular_cartilage_stem...

   Articular cartilage stem cell paste grafting was initially described by Kevin R. Stone M.D., a San Francisco-based orthopedic surgeon, in 1997 . The technique was devised in response to reports that many of the contemporary cartilage restoration procedures lead to the development of fibrocartilage, not true hyaline articular cartilage. Knowing ...

6. Stem-cell therapy - Wikipedia

   en.wikipedia.org/wiki/Stem-cell_therapy

   Stem-cell therapy uses stem cells to treat or prevent a disease or condition. [1] As of 2024, the only FDA-approved therapy using stem cells is hematopoietic stem cell transplantation. [2] [3] This usually takes the form of a bone marrow or peripheral blood stem cell transplantation, but the cells can also be derived from umbilical cord blood.

7. Hematopoietic stem cell transplantation - Wikipedia

   en.wikipedia.org/wiki/Hematopoietic_stem_cell...

   Stem-cell transplantation was pioneered using bone marrow-derived stem cells by a team at the Fred Hutchinson Cancer Research Center from the 1950s through the 1970s led by E. Donnall Thomas, whose work was later recognized with a Nobel Prize in Physiology or Medicine. Thomas' work showed that bone-marrow cells infused intravenously could ...