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  2. Grapefruit–drug interactions - Wikipedia

    en.wikipedia.org/wiki/Grapefruit–drug_interactions

    The effects last because grapefruit-mediated inhibition of drug metabolizing enzymes, like CYP3A4, is irreversible; [30] that is, once the grapefruit has "broken" the enzyme, the intestinal cells must produce more of the enzyme to restore their capacity to metabolize drugs that the enzyme is used to metabolize. [19]

  3. Hypothyroidism - Wikipedia

    en.wikipedia.org/wiki/Hypothyroidism

    Hypothyroidism (also called underactive thyroid, low thyroid or hypothyreosis) is a disorder of the endocrine system in which the thyroid gland does not produce enough thyroid hormones. [3] It can cause a number of symptoms, such as poor ability to tolerate cold , extreme fatigue, muscle aches , constipation , slow heart rate , depression , and ...

  4. This Is The Least Healthy Fruit, CDC Says - AOL

    www.aol.com/least-healthy-fruit-cdc-says...

    The least healthy fruit of all of the powerhouse fruits is the white grapefruit, according to the CDC. It scored 10.47 on the agency's ranking, compared to a perfect 100 for watercress .

  5. Thyroid disease - Wikipedia

    en.wikipedia.org/wiki/Thyroid_disease

    Certain medications can have the unintended side effect of affecting thyroid function. While some medications can lead to significant hypothyroidism or hyperthyroidism and those at risk will need to be carefully monitored, some medications may affect thyroid hormone lab tests without causing any symptoms or clinical changes, and may not require treatment.

  6. Signs and symptoms of Graves' disease - Wikipedia

    en.wikipedia.org/wiki/Signs_and_symptoms_of...

    In older patients, emotional instability may be less evident, or depression may occur, and the symptoms and signs are manifestly circulatory. In many, the thyroid is not readily palpable. [4] Symptoms such as rapid heart rate, shortness of breath on exertion, and edema may predominate. Older patients also tend to have more weight loss and less ...

  7. Thyrotoxic myopathy - Wikipedia

    en.wikipedia.org/wiki/Thyrotoxic_myopathy

    Administering the radioactive isotope causes the thyroid to take in the lethal iodine and quickly radiation destroys it. [12] Typically overproduction of thyroxine using radio-iodine is blocked with one dose. The drawback to this treatment is the thyroid gland is completely destroyed and patients often develop hypothyroidism. Some do so only a ...

  8. The Sneaky Sign of Inflammation You Shouldn't Ignore - AOL

    www.aol.com/sneaky-sign-inflammation-shouldnt...

    Here are some symptoms everyone should be aware of: Rashes You may not think of your skin as an organ, but it is — and it can be affected by inflammation just like any other organ.

  9. Iodine deficiency - Wikipedia

    en.wikipedia.org/wiki/Iodine_deficiency

    Iodine deficiency is a lack of the trace element iodine, an essential nutrient in the diet.It may result in metabolic problems such as goiter, sometimes as an endemic goiter as well as congenital iodine deficiency syndrome due to untreated congenital hypothyroidism, which results in developmental delays and other health problems.

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