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Levetiracetam, sold under the brand name Keppra among others, is a novel antiepileptic drug [7] used to treat epilepsy. [8] It is used for partial-onset , myoclonic , or tonic–clonic seizures, [ 7 ] and is taken either by mouth as an immediate or extended release formulation or by injection into a vein .
Food-grade lubricants are specialized industrial lubricants designed for use in environments where there is potential for incidental contact with food or beverages. These lubricants are used to ensure both the proper functioning of machinery and the safety of the products being processed.
The Food Protection Committee started in 1961 to provide objective quality standards for food-grade chemicals. Parts of the first edition were published in loose-leaf form between 1963 and 1966. The scope of the first edition is limited to substances amenable to chemical characterization or biological standardization which are added directly to ...
This potentially hepatotoxic botanical use, researchers say, is similar to the estimated number of people prescribed potentially hepatotoxic drugs such as nonsteroidal anti-inflammatory drugs ...
For the study, researchers from the University of Michigan analyzed data from six herbal supplements previously considered potentially hepatotoxic (toxic to the liver), including ashwagandha ...
A hepatotoxin (Gr., hepato = liver) is a toxic chemical substance that damages the liver.. It can be a side-effect, but hepatotoxins are also found naturally, such as microcystins and pyrrolizidine alkaloids, or in laboratory environments, such as carbon tetrachloride, or far more pervasively in the form of ethanol (drinking alcohol).
Furthermore, the researchers estimated that 15.6 million U.S. adults have taken at least one herbal supplement in the last 30 days that might be hepatotoxic or damaging to their liver.
Hepatotoxicity may manifest as triglyceride accumulation, which leads to either small-droplet (microvesicular) or large-droplet (macrovesicular) fatty liver. There is a separate type of steatosis by which phospholipid accumulation leads to a pattern similar to the diseases with inherited phospholipid metabolism defects (e.g., Tay–Sachs disease )