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  2. Lesch–Nyhan syndrome - Wikipedia

    en.wikipedia.org/wiki/Lesch–Nyhan_syndrome

    Allopurinol is taken orally, at a typical dose of 3–20 mg/kg per day. The dose is then adjusted to bring the uric acid level down into the normal range (<3 mg/dL). Most affected individuals can be treated with allopurinol all through life. [citation needed] No medication is effective in controlling the extrapyramidal motor features of the ...

  3. Allopurinol - Wikipedia

    en.wikipedia.org/wiki/Allopurinol

    Common side effects when used orally include itchiness and rash. [7] Common side effects when used by injection include vomiting and kidney problems. [7] While not recommended historically, starting allopurinol during an attack of gout appears to be safe. [8] [9] In those already on the medication, it should be continued even during an acute ...

  4. Lesinurad/allopurinol - Wikipedia

    en.wikipedia.org/wiki/Lesinurad/allopurinol

    Lesinurad/allopurinol (trade name Duzallo) is a fixed-dose combination drug for the treatment of gout. [1] It contains 200 mg of lesinurad and 300 mg of allopurinol.In August 2017, the US Food and Drug Administration approved it for the treatment of hyperuricemia associated with gout in patients for whom target serum uric acid levels have not been achieved with allopurinol alone. [2]

  5. Defined daily dose - Wikipedia

    en.wikipedia.org/wiki/Defined_Daily_Dose

    The defined daily dose (DDD) is a statistical measure of drug consumption, defined by the World Health Organization (WHO) Collaborating Centre for Drug Statistics Methodology. It is defined in combination with the ATC Code drug classification system for grouping related drugs. The DDD enables comparison of drug usage between different drugs in ...

  6. Factbox-Who received the longest jail terms in the Gisele ...

    www.aol.com/news/factbox-received-longest-jail...

    A French court found all 51 defendants guilty on Thursday in a mass rape case including Dominique Pelicot, who repeatedly drugged his then wife, Gisele, and allowed dozens of strangers into the ...

  7. Lesinurad - Wikipedia

    en.wikipedia.org/wiki/Lesinurad

    Lesinurad (brand name Zurampic) is a urate transporter inhibitor for treating high blood uric acid levels associated with gout. [2] It is recommended only as an adjuvant with either allopurinol or febuxostat when these medications are not sufficient.

  8. Supreme Court allows multibillion-dollar class action to ...

    www.aol.com/supreme-court-allows-multibillion...

    The Supreme Court is allowing a multibillion-dollar class action investors’ lawsuit to proceed against Facebook parent Meta, stemming from the privacy scandal involving the Cambridge Analytica ...

  9. Sharp downgrades to US unit labor costs bode well for ...

    www.aol.com/news/us-third-quarter-unit-labor...

    WASHINGTON (Reuters) -U.S. unit labor costs grew far less than initially thought in the third quarter, pointing to a still favorable inflation outlook even though price increases have not ...