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In 1981, a paper by Gosselin estimated that the lethal dose is between 50 and 500 mg/kg. Doses as high as 15–20 mg/kg are taken by some recreational users. A single case study suggests that the antidote to dextromethorphan overdose is naloxone, administered intravenously. [17]
Dextromethorphan, sold under the brand name Robitussin among others, is a cough suppressant used in many cough and cold medicines. [6] In 2022, the US Food and Drug Administration (FDA) approved the combination dextromethorphan/bupropion to serve as a rapid-acting antidepressant in people with major depressive disorder .
Repeated administration of a medication is also different from single dosing, as many drugs have active metabolites that can build up in the body. [6] Patient variables such as sex, age, and organ function may also influence the effect of the drug on the system. These variables are rarely included in equianalgesic charts. [7] [3] [8]
The settlement covers Robitussin purchasers from Feb. 16, 2016 to the present. Payouts may total $1.50 to $4.75 per claim, depending on the number of claims. As much as $2.05 million, or 46% of ...
The maker of Robitussin cough syrup is recalling several lots of products containing honey due to contamination that could pose a serious risk to people with weakened immune systems.
Some brand names include: Benylin, Sudafed, Robitussin and Vicks among others. [35] Most contain a number of active ingredients. [4] The Thai company Hatakabb produces the Takabb Anti-Cough Pill, which is a Chinese herbal medication. [36] Sudafed is a brand manufactured by McNeil Laboratories.
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