Search results
Results from the WOW.Com Content Network
Benzamide is an organic compound with the chemical formula of C 7 H 7 NO. It is the simplest amide derivative of benzoic acid . In powdered form, it appears as a white solid, while in crystalline form, it appears as colourless crystals. [ 5 ]
This page was last edited on 19 December 2023, at 00:04 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.
Benzamidine is a reversible competitive inhibitor of trypsin, trypsin-like enzymes, and serine proteases. [4]It is often used as a ligand in protein crystallography to prevent proteases from degrading a protein of interest.
Antipsychotics by class Generic name Brand names Chemical class ATC code Typical antipsychotics; Acepromazine: Atravet, Acezine: phenothiazine: N05AA04
Sultopride (trade names Barnetil, Barnotil, Topral) is an atypical antipsychotic of the benzamide chemical class used in Europe, Japan, and Hong Kong for the treatment of schizophrenia. [2] [3] [4] It was launched by Sanofi-Aventis in 1976. [2] Sultopride acts as a selective D 2 and D 3 receptor antagonist. [5]
Trimethobenzamide is marketed under the brand names Tebamide and Tigan, manufactured by GlaxoSmithKline and King Pharmaceuticals, respectively.It is available as oral capsules and injectable formulations.
It is a benzamide HDI and inhibits Class I HDAC1, HDAC2, HDAC3, as well as Class IIb HDAC10. [ 3 ] Tucidinostat is approved by the Chinese FDA for relapsed or refractory peripheral T-cell lymphoma (PTCL) and has orphan drug status in Japan.
Benzamide and its derivatives are highly water-soluble, and because of their polarity are believed to cross the blood–brain barrier via carrier-mediated transport. [14] Elimination of tiapride, mostly in its original form, occurs through renal excretion with a half-life of 3 to 4 hours.