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Carcinoembryonic antigen (CEA) describes a set of highly-related glycoproteins involved in cell adhesion. CEA is normally produced in gastrointestinal tissue during fetal development, but the production stops before birth. Consequently, CEA is usually present at very low levels in the blood of healthy adults (about 2–4 ng/mL). [2]
In the literature, CEACAM5 is often used as a synonym for cancer embryonic antigen (CEA), a well-known biomarker of many types of malignancies, such as colorectal cancer and non-small-cell lung cancer. [4] [5] Its primary function in the embryonic intestine and colon tumors is adhesion between epithelial cells. [6]
Carbohydrate antigen 19-9 (CA19-9), also known as sialyl-Lewis A, is a tetrasaccharide which is usually attached to O-glycans on the surface of cells. It is known to play a role in cell-to-cell recognition processes. It is also a tumor marker used primarily in the management of pancreatic cancer. [1]
Carcinoembryonic antigen-related cell adhesion molecule 19 is a carcinoembryonic antigen encoded in the human by the CEACAM19 gene. The expression of this gene is associated with breast cancer [ 5 ] and colorectal cancer [ 6 ]
Mainly pancreatic cancer, but also colorectal cancer and other types of gastrointestinal cancer. [12] CA-125: Mainly ovarian cancer, [13] but may also be elevated in for example endometrial cancer, fallopian tube cancer, lung cancer, breast cancer and gastrointestinal cancer. [14] Calcitonin: medullary thyroid carcinoma [15] Calretinin
Arcitumomab recognizes carcinoembryonic antigen (CEA), an antigen over-expressed in 95% of colorectal cancers. [3] Consequently, the antibody accumulates in such tumours together with the radioisotope, which emits photons.
n/a Ensembl ENSG00000280501 ENSG00000007306 n/a UniProt Q14002 n/a RefSeq (mRNA) NM_006890 NM_001291485 n/a RefSeq (protein) NP_001278414 NP_008821 n/a Location (UCSC) Chr 19: 41.67 – 41.71 Mb n/a PubMed search n/a Wikidata View/Edit Human Carcinoembryonic antigen-related cell adhesion molecule 7 is a protein that in humans is encoded by the CEACAM7 gene. References ^ a b c ENSG00000007306 ...
Carcinoembryonic antigen (CEA) colorectal cancer (diagnosis) Amatuximab [16] mab: chimeric: mesothelin: cancer Amivantamab: Rybrevant: BsAb: human: Epidermal growth factor receptor (EGFR), cMet: Y: non-small cell lung cancer: Anatumomab mafenatox [17] Fab: mouse: Tumor-associated glycoprotein 72 (TAG-72) non-small cell lung cancer ...
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