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  2. Aminoglycoside - Wikipedia

    en.wikipedia.org/wiki/Aminoglycoside

    Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside .

  3. G418 - Wikipedia

    en.wikipedia.org/wiki/G418

    G418 (geneticin) is an aminoglycoside antibiotic similar in structure to gentamicin B1.It is produced by Micromonospora rhodorangea. [1] G418 blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells. [1]

  4. List of antibiotics - Wikipedia

    en.wikipedia.org/wiki/List_of_antibiotics

    Generic name Brand names Common uses [4] Possible side effects [4] Mechanism of action Aminoglycosides; Amikacin: Amikin: Infections caused by Gram-negative bacteria, such as Escherichia coli and Klebsiella particularly Pseudomonas aeruginosa. Effective against aerobic bacteria (not obligate/facultative anaerobes) and tularemia. All ...

  5. Hygromycin B - Wikipedia

    en.wikipedia.org/wiki/Hygromycin_B

    Hygromycin B was originally developed in the 1950s for use with animals and is still added into swine and chicken feed as an anthelmintic or anti-worming agent (product name: Hygromix). Hygromycin B is produced by Streptomyces hygroscopicus, a bacterium isolated in 1953 from a soil sample. Resistance genes were discovered in the early 1980s.

  6. Gentamicin - Wikipedia

    en.wikipedia.org/wiki/Gentamicin

    Gentamicin is a type of aminoglycoside [5] and works by disrupting the ability of the bacteria to make proteins, which typically kills the bacteria. [5] Gentamicin is naturally produced by the bacterium Micromonospora purpurea, [9] [5] was patented in 1962, approved for medical use in 1964. [10]

  7. Kanamycin kinase - Wikipedia

    en.wikipedia.org/wiki/Kanamycin_kinase

    Aminoglycoside-3'-phosphotransferase (APH(3')), also known as aminoglycoside kinase, is an enzyme that primarily catalyzes the addition of phosphate from ATP to the 3'-hydroxyl group of a 4,6-disubstituted aminoglycoside, such as kanamycin. [2]

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  9. Kanamycin A - Wikipedia

    en.wikipedia.org/wiki/Kanamycin_A

    Kanamycin is in the aminoglycoside family of medications. [3] It has the weakest antibacterial capabilities of all compounds in this family when used clinically, which is partially due to its increased toxicity in comparison to other aminoglycosides. [5] It works by blocking the production of proteins that are required for bacterial survival. [3]