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Saccharomyces boulardii is a tropical yeast first isolated from lychee and mangosteen peels in 1923 by French scientist Henri Boulard. Although early reports claimed distinct taxonomic , metabolic, and genetic properties, [ 1 ] S. boulardii is a grouping of S. cerevisiae strains, all sharing a >99% genomic relatedness.
The strain Saccharomyces cerevisiae var. boulardii is industrially manufactured and used clinically as a medication. Several clinical and experimental studies have shown that S. cerevisiae var. boulardii is, to lesser or greater extent, useful for prevention or treatment of several gastrointestinal diseases. [71]
One example is Saccharomyces cerevisiae, which is used in making bread, wine, and beer, and for human and animal health. Other members of this genus include the wild yeast Saccharomyces paradoxus that is the closest relative to S. cerevisiae, Saccharomyces bayanus, used in making wine, and Saccharomyces cerevisiae var. boulardii, used in medicine.
S. boulardii has been shown to reduce the symptoms of acute diarrhea, [98] reduce the chance of infection by Clostridium difficile (often identified simply as C. difficile or C. diff), [99] reduce bowel movements in diarrhea-predominant IBS patients, [100] and reduce the incidence of antibiotic-, traveler's-, and HIV/AIDS-associated diarrheas ...
Signs and symptoms of CDI range from mild diarrhea to severe life-threatening inflammation of the colon. [16]In adults, a clinical prediction rule found the best signs to be significant diarrhea ("new onset of more than three partially formed or watery stools per 24-hour period"), recent antibiotic exposure, abdominal pain, fever (up to 40.5 °C or 105 °F), and a distinctive foul odor to the ...
Saccharomycotina is a subdivision (subphylum) of the division (phylum) Ascomycota in the kingdom Fungi. [2] [3] It comprises most of the ascomycete yeasts.The members of Saccharomycotina reproduce by budding and they do not produce ascocarps (fruiting bodies).
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