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Side effects of pseudoephedrine include insomnia, elevated heart rate, increased blood pressure, restlessness, dizziness, anxiety, and dry mouth, among others. [ 21 ] [ 2 ] [ 1 ] [ 22 ] Rarely, pseudoephedrine has been associated with serious cardiovascular complications like heart attack and hemorrhagic stroke .
Phenylephrine, sold under the brand names Neosynephrine and Sudafed PE among others, is a medication used as a decongestant for uncomplicated nasal congestion in the form of a nasal spray or oral tablet, [5] to dilate the pupil, to increase blood pressure given intravenously in cases of low blood pressure, and to relieve hemorrhoids as a suppository.
The effects are not limited to the nose, and these medicines may cause hypertension (high blood pressure) through vasoconstriction; it is for this reason that people with hypertension are advised to avoid them. Most decongestants, however, are not pronounced stimulants, due to lack of response from the other adrenoreceptors.
Phenylephrine ‘is extensively broken down in the liver, resulting in little to no pharmacological effect’
[2] [3] However, higher doses of levmetamfetamine, for instance 0.25 to 0.5 mg/kg (mean doses of ~18–37 mg) intravenously, have been reported to produce significant pharmacological effects, including increased heart rate and blood pressure, increased respiration rate, and subjective effects like intoxication and drug liking.
Common side effects include trouble sleeping, anxiety, headache, hallucinations, high blood pressure, fast heart rate, loss of appetite, and urinary retention. [11] Serious side effects include stroke and heart attack. [11] While likely safe in pregnancy, its use in this population is poorly studied. [12] [13] Use during breastfeeding is not ...
Due to its sympathomimetic effects, it should not be used by people with high blood pressure, or other heart problems. Extended usage of xylometazoline can result in decreased effectiveness or a buildup of tolerance against the drug. [12]
With continued use, steroids have dangerous side effects which include, but are not limited to: high blood pressure, diabetes, weight gain, osteoporosis, stomach ulcers, adrenal insufficiency ...
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